Effects of Uniaxial Cyclic Strain on Endothelial Progenitor Cells [PDF]
Despite the high prevalence of calcific aortic valve disease (CAVD), the underlying mechanisms of pathogenesis have not been found yet. Therefore, it is extremely important to study CAVD and understand how it develops.
Zeballos Castro, Maria Alejandra
core +2 more sources
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Análisis de la expresión transgénica en plantas, mediante la técnica Western Blotting
La transformación de plantas mediante la tecnología del DNA recombinante es un proceso cuyo resultado debe evaluarse a nivel molecular aplicando técnicas de análisis de la expresión transgénica.
Leidy Andrea Ávila Sánchez+1 more
doaj
Induction of MET Receptor Tyrosine Kinase Down-Regulation through Antibody-Mediated Receptor Clustering [PDF]
The proto-oncoprotein MET is a receptor tyrosine kinase that plays a key role in cancer cell growth and invasion. We have used fluorescence-tagged antibodies to activate MET in live serum-starved glioblastoma cells and monitor the fate of antibody-bound ...
Adam Dick+4 more
core +3 more sources
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
We evaluated the effectiveness of serological and parasitological methods for cutaneous leishmaniasis (CL) diagnosis in patients from the central region of Paraná state, southern Brazil.
Regiane Szargiki+5 more
doaj +1 more source
Heparanase-1 activities in the development of laser induced choroidal neovascularization
AIM:To investigate the role of heparanase-1 in laser-induced choroidal neovascularization (CNV).METHODS:Experimental CNV was induced by krypton laser photocoagulation in 15 male Brown Norway rats.
Bao-Ke Hou, Wei-Qiang Tang
doaj +1 more source
Western blot (immunoblot) assay of small, round-structured virus associated with an acute gastroenteritis outbreak in Tokyo [PDF]
Yujiro Hayashi+7 more
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Qualitative and quantitative analyses of Epstein-Barr virus early antigen diffuse component by western blotting enzyme-linked immunosorbent assay with a monoclonal antibody [PDF]
J.-C. Lin, Etsuyo I. Choi, J S Pagano
openalex +1 more source