Results 301 to 310 of about 2,778,272 (379)

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

open access: yesAdvanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li   +7 more
wiley   +1 more source

Dual‐Selective Terahertz‐Nanodisc Metasurfaces for Exploring Neurotransmitter Dynamics beyond Spectral Limitations

open access: yesAdvanced Materials, EarlyView.
Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim   +6 more
wiley   +1 more source

Transparent Temperature Sensors for Photothermal Neuromodulation: Advances, Challenges, and Future Directions

open access: yesAdvanced Materials Interfaces, EarlyView.
Photothermal neuromodulation is a promising technique for versatile neural signal study and treatment development. To further develop these technologies and optimize their effectiveness, transparent electrical temperature sensors with high thermal sensitivity and resolution are essential for accurately monitoring temperature changes during ...
Jee Woong Lee   +7 more
wiley   +1 more source

GelMA/AgNWs Hydrogel Combined with Electrical Stimulation Effectively Promotes Skin Wound Healing

open access: yesAdvanced Materials Interfaces, EarlyView.
The doped AgNWs in GelMA hydrogel prevent the wound from being infected and introduce the electrical field into the wound region. COMSOL simulation guides the introduced electric field to be conducive to promoting cell migration and proliferation. Thus, the GelMA/AgNWs hydrogel combined with ES effectively accelerated the healing process of skin wounds.
Xiaoxuan Hou   +6 more
wiley   +1 more source

Red Blood Cell Membrane‐Camouflaged Red Phosphorus‐Modified C3N4 for Enhanced Tumoral Photodynamic Therapy

open access: yesAdvanced Materials Interfaces, EarlyView.
Photodynamic therapy (PDT) faces clinical challenges due to poor tumor targeting and systemic toxicity. Herein, a biomimetic C3N4‐RP@RBCm nanoplatform is developed via erythrocyte membrane encapsulation, enabling CD47‐mediated immune evasion and EPR‐driven tumor accumulation.
Jiaxiu Liu   +9 more
wiley   +1 more source

In Situ Monitoring and Electrical Modulation of Cellular Behaviors Directly at the Cell–Electrode Interface

open access: yesAdvanced Materials Interfaces, EarlyView.
This study presents a platform for simultaneous monitoring and electrical control of cellular responses at the cell–electrode interface. The platform delivers tunable yet uniform electrical cues to cells, revealing that optimal electrical stimulation (ES) conditions vary across cell types.
Khandoker Asiqur Rahaman   +7 more
wiley   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

open access: yesAdvanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah   +6 more
wiley   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

open access: yesAdvanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı   +7 more
wiley   +1 more source

Automated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers

open access: yesAdvanced Therapeutics, EarlyView.
Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy