Many geological, environmental, and archaeological pieces of evidence in the Egyptian Western Desert point to the important role that the desert played in the cultural development along the Nile, especially during the Late Prehistoric Period. The process
Nourhan Moustafa
doaj +1 more source
Following the rivers: historical reconstruction of California voles Microtus californicus (Rodentia: Cricetidae) in the deserts of eastern California [PDF]
The California vole, Microtus californicus, restricted to habitat patches where water is available nearly year-round, is a remnant of the mesic history of the southern Great Basin and Mojave deserts of eastern California.
Conroy, CJ +5 more
core +3 more sources
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
The Tibetan Plateau space-based tropospheric aerosol climatology: 2007–2020 [PDF]
A comprehensive and robust dataset of tropospheric aerosol properties is important for understanding the effects of aerosol–radiation feedback on the climate system and reducing the uncertainties of climate models.
H. Pan +30 more
doaj +1 more source
Neotropical Bird Migration During The Ice Ages: Orientation And Ecology [PDF]
Reconstruction of breeding habitat of North American Neotropical migrants 18,000 years ago and 9,000 years ago indicated major shifts in both location and composition of plant communities relative to present conditions.
Webb, T., III +1 more
core +2 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
The Mongolian–Transbaikalian region of the Central Asia is known for its wide range of intracontinental ecosystems from desert through steppe to taiga forest and mountain tundra.
A. M. Khubanova +2 more
doaj +1 more source
Terrestrial climate variability and seasonality changes in the Mediterranean region between 15 000 and 4000 years BP deduced from marine pollen records [PDF]
Pollen-based climate reconstructions were performed on two high-resolution pollen marines cores from the Alboran and Aegean Seas in order to unravel the climatic variability in the coastal settings of the Mediterranean region between 15 000 and 4000 ...
Combourieu-Nebout, Nathalie +6 more
core +4 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Scientific value and utility of geo(morpho)sites, with a case of the El-Medallat hills in Egypt
Geological and geomorphological heritage (geoheritage) has many aspects, some of which are yet to be fully understood. Particularly, a scientific value of geo(morpho)sites is defined differently and established with not fully satisfying approaches.
Dmitry A. Ruban, Emad S. Sallam
doaj +1 more source

