Results 141 to 150 of about 1,843,358 (306)
Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis
Advanced Science, EarlyView.The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang +14 more
wiley +1 more source
The Situation in the South-East of Ukraine: the Geopolitical Goals of Actors
Евразийская интеграция: экономика, право, политика, 2019 The article discusses the geopolitical goals of the main actors involved in the process of constructing a situation in the South-East of Ukraine. The configuration arrangement of actors is revealed, and a possible approach to forecasting the development ...
Maxim N. Stebakov
doaj
Demographic Diversity and Convergence in Europe, 1918-1990 [PDF]
The study investigates how Hungarian demographic development from the end of World War I to 1990 related to the changes that took place in Western Europe, and in which areas and in what periods can divergence or convergence be observed.
Béla Tomka
core
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Welfare Policies in the UNECE Region: Why so Different? [PDF]
This paper provides the text of the Gunnar Myrdal Lecture presented at the U.N. Palais des Nations in 2006. It provides an analysis of why different countries in the western world have chosen different models of the welfare state.
Alberto Alesina
core
Advanced Science, EarlyView.Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li +11 more
wiley +1 more source
Advanced Science, EarlyView.The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
The world wide spread of space technology [PDF]
Space technological capabilities and developments in US, USSR, Western Europe, Japan, China, and developing ...
Hoagland, J. H., Skolnikoff, E. B.
core +1 more source
Advanced Science, EarlyView.A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil +7 more
wiley +1 more source
Advanced Science, EarlyView.DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang +11 more
wiley +1 more source