Results 1 to 10 of about 17,753,198 (231)
Do Mixtures of Beads with Different Sizes Improve Wet Stirred Media Milling of Drug Suspensions? [PDF]
Pharmaceutics, 2023 The impacts of bead sizes and bead mixtures on breakage kinetics, the number of milling cycles applied to prevent overheating, and power consumption during the nanomilling of drug (griseofulvin) suspensions were investigated from both an experimental and
Gulenay Guner +6 more
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A Novel PBM for Nanomilling of Drugs in a Recirculating Wet Stirred Media Mill: Impacts of Batch Size, Flow Rate, and Back-Mixing [PDF]
PharmaceuticsWe examined the evolution of fenofibrate (FNB, drug) particle size distribution (PSD) during the production of nanosuspensions via wet stirred media milling (WSMM) with a cell-based population balance model (PBM).
Hamidreza Heidari +5 more
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Kinetic and Microhydrodynamic Modeling of Fenofibrate Nanosuspension Production in a Wet Stirred Media Mill [PDF]
Pharmaceutics, 2021 This study examined the impact of stirrer speed and bead material loading on fenofibrate particle breakage during wet stirred media milling (WSMM) via three kinetic models and a microhydrodynamic model.
Gulenay Guner +2 more
doaj +3 more sources
Visible Light Active Natural Rutile Photocatalyst Obtained via Nano Milling [PDF]
MoleculesNatural rutile is a widely available titanium mineral which shows great potential as a photocatalyst for environmental remediation when processed correctly.
Kata Saszet +7 more
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Biology and Life Sciences Forum, 2023 Sustainable corn starch nanoparticles were prepared using media milling to stabilize omega-3-rich Pickering emulsions based on chia oil. The milling conditions were as follows: 24 h (milling time), 0.4–0.6 mm (bead diameter), 1600 rpm (impeller speed ...
María G. Bordón +8 more
doaj +1 more source
Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions
Pharmaceutics, 2022 Amorphous solid dispersions (ASD) are one of the most prominent formulation approaches to overcome bioavailability issues that are often presented by new poorly soluble drug candidates. State-of-the art manufacturing techniques include hot melt extrusion
Malin Hermeling +4 more
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Frontiers in Chemistry, 2022 The biocompatible nanosuspension of CuS nanoparticles (NPs) using bovine serum albumin (BSA) as a capping agent was prepared using a two-stage mechanochemical approach. CuS NPs were firstly synthetized by a high-energy planetary ball milling in 15 min by
Martin Stahorský +11 more
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Pharmaceutics, 2022 Although temperature can significantly affect the stability and degradation of drug nanosuspensions, temperature evolution during the production of drug nanoparticles via wet stirred media milling, also known as nanomilling, has not been studied ...
Gulenay Guner +4 more
doaj +1 more source
Electro-Hydrodynamic Drop-on-Demand Printing of Aqueous Suspensions of Drug Nanoparticles
Pharmaceutics, 2020 We demonstrate the ability to fabricate dosage forms of a poorly water-soluble drug by using wet stirred media milling of a drug powder to produce an aqueous suspension of nanoparticles and then print it onto a porous biocompatible film.
Ezinwa Elele +5 more
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Nanomilling of Drugs for Bioavailability Enhancement: A Holistic Formulation-Process Perspective
Pharmaceutics, 2016 Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet media milling followed by various drying processes has become a
Meng Li +3 more
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