Results 1 to 10 of about 16,685 (68)

The Nanostructure of Polymer-Active Principle Microparticles Produced by Supercritical CO₂ Assisted Processing

Nanomaterials, 2022
Traditional and supercritical CO2 assisted processes are frequently used to produce microparticles formed by a biopolymer containing an active principle to improve the bioavailability of the active principle.
Ernesto Reverchon, Mariarosa Scognamiglio, Lucia Baldino   +2 more
doaj   +1 more source

Do Mixtures of Beads with Different Sizes Improve Wet Stirred Media Milling of Drug Suspensions?

Pharmaceutics, 2023
The impacts of bead sizes and bead mixtures on breakage kinetics, the number of milling cycles applied to prevent overheating, and power consumption during the nanomilling of drug (griseofulvin) suspensions were investigated from both an experimental and
Gulenay Guner, Mirsad Mehaj, Natasha Seetharaman, Sherif Elashri, Helen F. Yao, Donald J. Clancy, Ecevit Bilgili   +6 more
doaj   +1 more source

Predicting the Temperature Evolution during Nanomilling of Drug Suspensions via a Semi-Theoretical Lumped-Parameter Model

Pharmaceutics, 2022
Although temperature can significantly affect the stability and degradation of drug nanosuspensions, temperature evolution during the production of drug nanoparticles via wet stirred media milling, also known as nanomilling, has not been studied ...
Gulenay Guner, Dogacan Yilmaz, Helen F. Yao, Donald J. Clancy, Ecevit Bilgili   +4 more
doaj   +1 more source

Preparation and Characterization of Spray-Dried Hybrid Nanocrystal–Amorphous Solid Dispersions (HyNASDs) for Supersaturation Enhancement of a Slowly Crystallizing Drug

Nanomaterials, 2023
We prepared hybrid nanocrystal–amorphous solid dispersions (HyNASDs) to examine their supersaturation capability in the release of a poorly soluble drug, itraconazole (ITZ), a slow crystallizer during dissolution.
Mahbubur Rahman, Keanu Radgman, James Tarabokija, Stephanie Ahmad, Ecevit Bilgili   +4 more
doaj   +1 more source

Nanoceria as Safe Contrast Agents for X-ray CT Imaging

Nanomaterials, 2023
Cerium oxide nanoparticles (CeO2NPs) have exceptional catalytic properties, rendering them highly effective in removing excessive reactive oxygen species (ROS) from biological environments, which is crucial in safeguarding these environments against ...
Ana García, Juan Antonio Cámara, Ana María Boullosa, Muriel F. Gustà, Laura Mondragón, Simó Schwartz, Eudald Casals, Ibane Abasolo, Neus G. Bastús, Víctor Puntes   +9 more
doaj   +1 more source

Gold Nanoparticles as Drug Carriers: The Role of Silica and PEG as Surface Coatings in Optimizing Drug Loading

Micromachines, 2023
The use of gold nanoparticles as drug delivery systems has received increasing attention due to their unique properties, such as their high stability and biocompatibility. However, gold nanoparticles have a high affinity for proteins, which can result in
José Luis Carreón González, Perla Elvia García Casillas, Christian Chapa González   +2 more
doaj   +1 more source

Fabrication and evaluation magnetic nanoparticles loaded with cefixime

Journal of Contemporary Pharmacy, 2021
Background. Bacterial infections are an important cause of serious health issues worldwide. Various antibacterial drugs have been developed but they have numerous side effects.
Kanza Amjad, Ume Habiba, Talib Hussain, Safiullah Khan, Muhammad Akram Choohan   +4 more
doaj   +1 more source

Preparation and characterization of magnetic nanoparticles loaded with antimicrobial agent

Journal of Contemporary Pharmacy, 2022
Background: Bacterial infections are an important cause of serious health issues worldwide. Various antibacterial drugs have been developed but they have numerous side effects.
Kanza Amjad, Muhammad Naeem Aamir, Muhammad Akram Choohan, Ume Habiba, Saif Ur Rehman   +4 more
doaj   +1 more source

Nanomilling of Drugs for Bioavailability Enhancement: A Holistic Formulation-Process Perspective

Pharmaceutics, 2016
Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet media milling followed by various drying processes has become a
Meng Li, Mohammad Azad, Rajesh Davé, Ecevit Bilgili   +3 more
doaj   +1 more source

Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance

Frontiers in Molecular Biosciences, 2020
Nanotechnology has been extensively studied and exploited for cancer treatment as nanoparticles can play a significant role as a drug delivery system.
Yihan Yao, Yunxiang Zhou, Lihong Liu, Yanyan Xu, Yanyan Xu, Qiang Chen, Yali Wang, Shijie Wu, Yongchuan Deng, Jianmin Zhang, Anwen Shao   +10 more
doaj   +1 more source