Results 41 to 50 of about 2,524,657 (288)
Targeting of drugs and nanoparticles to tumors [PDF]
The Journal of Experimental Medicine, 2010 The various types of cells that comprise the tumor mass all carry molecular markers that are not expressed or are expressed at much lower levels in normal cells. These differentially expressed molecules can be used as docking sites to concentrate drug conjugates and nanoparticles at tumors. Specific markers in tumor vessels are particularly well suited
Ruoslahti, Erkki +2 more
openaire +6 more sources
Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]
, 2003 Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C. +3 more
core +1 more source
Remotely triggered scaffolds for controlled release of pharmaceuticals [PDF]
, 2013 Fe3O4-Au hybrid nanoparticles (HNPs) have shown increasing potential for biomedical applications such as image guided stimuli responsive drug delivery.
McGarvey, David J. +7 more
core +1 more source
, 2023 An escalating tendency prevails to manipulate gold-based nanoparticles decorated on their surfaces with different types of carbohydrates or glycopolymers for the development of versatile nanoplatforms—the so-called glyco-gold nanoparticles (GAuNPs) here ...
Yilmaz, Bengi, Akturk, Omer
core +1 more source
Bioengineering & Translational Medicine, 2021 Current drug delivery approaches for the treatment of cartilage disorders such as osteoarthritis (OA) remain inadequate to achieve sufficient drug penetration and retention in the dense cartilage matrix.
Xiangzhao Ai +7 more
doaj +1 more source
Investigating the effect of the stabilizer concentrations (1%, 2%, 3%, 4% and 5% PVA (polyvinyl alcohol)) on the surface properties of the nanoparticles and the drug delivery systems that are formed with the nanoparticles of 2% PLGA (poly(lactic-co-glycolic acid)), by solvent evaporation method. [PDF]
, 2013 Nanotechnology aims to manipulate characteristics of matter at atomic scale in order to improve drug delivery systems. The purpose of this extended essay is to investigate how surface properties of nanoparticles and drug delivery sytems of these ...
Ertürk, Mine Su
core +1 more source
PharmaceuticsWe examined the evolution of fenofibrate (FNB, drug) particle size distribution (PSD) during the production of nanosuspensions via wet stirred media milling (WSMM) with a cell-based population balance model (PBM).
Hamidreza Heidari +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Nanoparticles as drug delivery systems
Pharmacological Reports, 2012 Controlled drug delivery systems (DDS) have several advantages compared to the traditional forms of drugs. A drug is transported to the place of action, hence, its influence on vital tissues and undesirable side effects can be minimized. Accumulation of therapeutic compounds in the target site increases and, consequently, the required doses of drugs ...
Wilczewska, Agnieszka +3 more
openaire +3 more sources
Nano-carriers and their drug release
上海师范大学学报. 自然科学版, 2017 One of the hottest fields in biomedicine research is to encapsulate drugs and release them in particular organs by using nano-platform.Because nanoparticles can enter most cancer cells easily and accumulate inside the cells,drug-loaded nanoparticles with
Deng Guang +3 more
doaj +1 more source