Results 1 to 10 of about 386,825 (120)

A fluorescence sensor for nitroreductase detection in hypoxic cells and zebrafish

open access: yesResults in Chemistry, 2021
Nitroreductase (NTR) is a type of cytoplasmic enzyme that depends on flavin mononucleotide or flavin adenine dinucleotide, and that is widely present in tumor cells where it increases during hypoxia. NTR can effectively reduce aromatic nitro compounds to
Wan Sun   +7 more
doaj   +1 more source

Syntheses, crystal structure, thermal behavior, and anti-tumor activity of three ternary metal complexes with 2-chloro-5-nitrobenzoic acid and heterocyclic compounds

open access: yesHeterocyclic Communications, 2022
Three complexes, namely complex (1), complex (2), and complex (3), were synthesized and characterized by X-ray diffraction, thermogravimetric study, and elemental study.
Zhang Zhongyu   +6 more
doaj   +1 more source

Crystal structure of (1,10-phenanthroline-κ2N,N′)-bis(3-thiophenecarboxylato-κ2O,O′)copper(II), C22H14N2O4S2Cu

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2021
C22H14N2O4S2Cu, orthorhombic, Pbcn (no. 60), a = 20.171(7) Å, b = 9.684(3) Å, c = 10.372(4) Å, V = 2025.9(12) Å3, Z = 4, Rgt(F) = 0.0334, wRref(F2) = 0.0908, T = 273.15 K.
Zhang Zhongyu   +3 more
doaj   +1 more source

The crystal structure of aqua-bis(6-chloropicolinato-κ2N,O)copper(II), C12H8Cl2N2O5Cu

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2021
C12H8Cl2N2O5Cu, triclinic, P1‾$P‾{1}$ (no. 2), a = 6.800(2) Å, b = 9.086(3) Å, c = 11.363(4) Å, α = 86.701(6)°, β = 84.830(5)°, γ = 77.353(5)°, V = 681.7(4) Å3, Z = 2, Rgt(F) = 0.0250, wRref(F2) = 0.0655, T = 296(2) K.
Zhang Zhongyu   +2 more
doaj   +1 more source

A Translation of Technology: MicroCoat™ to Sustained Release Orally Disintegrating Tablets

open access: yesBritish Journal of Pharmacy, 2022
Orally disintegrating tablets (ODTs) comprising sustained release (SR) coated microparticles smaller than 250 µm provide an appealing dosage form for patients with dysphagia, offering a superior mouthfeel and highly convenient route of administration ...
Kavil Patel   +3 more
doaj   +1 more source

The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The understanding of toxicological and pharmacological profiles of nanomaterials is an important step for the development and clinical application of nanomedicines.
Ping-Xuan Dong   +11 more
doaj   +1 more source

Sustained-release drug delivery systems for the treatment of glaucoma [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
Glaucoma, a leading cause of irreversible blindness, affects more than 64 million people worldwide and is expected to grow in number due to the aging global population and enhanced methods of detection. Although topical therapies are often effective when
Natasha P. Kesav   +4 more
doaj   +1 more source

A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD

open access: yesAllergology International, 2006
Background: Theophylline is a useful drug for the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) recommend use of sustained-release theophylline products as controllers and of injectable aminophylline products as relievers ...
Sohei Makino   +7 more
doaj   +1 more source

Tramadol Steady-State Pharmacokinetics of Immediate-Release Capsules and Sustained-Release Tablets in Dogs

open access: yesFuture Pharmacology, 2022
Tramadol is a veterinary analgesic for dogs. In this study, the steady-state pharmacokinetics of a sustained-release (SR) tablet (Tramagetic OD®) and immediate-release capsules (IR) were compared. In a crossover design, six dogs received five doses of IR
Esther Winter   +4 more
doaj   +1 more source

Pseudo-zwitterionic microvesicles for sustained urea release [PDF]

open access: yesJournal of the Serbian Chemical Society, 2020
Zwitterionic microvesicles formed by catanionic system, based on sodium dodecyl sulfate and hexadecyltrimethyl ammonium bromide, have been investigated for sustained urea release using UV–visible absorption spectroscopy.
Bibi Iram   +4 more
doaj   +1 more source

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