Results 11 to 20 of about 386,974 (265)

Sustained-Release Corticosteroid Options [PDF]

Journal of Ophthalmology, 2014
Sustained-release corticosteroid treatment has shown to be a promising strategy for macular edema due to retinovascular disease (i.e., diabetes and retinal vein occlusion) and for the treatment of noninfectious posterior uveitis. Clinicians now have the option of three sustained-release corticosteroid implants: Ozurdex (Allergan Inc., Irvine, CA) which
Mariana Cabrera, Steven Yeh, Thomas A. Albini   +2 more
doaj   +3 more sources

PHARMACOKINETICS OF SUSTAINED RELEASE ASPIRIN [PDF]

British Journal of Clinical Pharmacology, 1978
Salivary salicylate concentrations were used to study the pharmacokinetics of a sustained release aspirin (SRA) in normal volunteers.The effect of fasting, food and metoclopramide were studied.Metoclopramide hastens absorption while a heavy meal delays absorption of SRA.The mean urinary recovery of aspirin in all the trials was 608 mg and the different
Brooks, P. M., Roberts, M. S., Patel, P.
openaire   +3 more sources

Sustained-release Corticosteroids for Uveitis [PDF]

Ocular Immunology and Inflammation, 2015
Corticosteroids constitute both first-line and important adjunctive therapy in patients with non-infectious uveitis.1,2 Three sustained-release corticosteroid dosage forms are currently available f...
Cunningham, E.T., Smet, M.D. de, Yeh, S., Albini, T.A., Zierhut, M.   +4 more
openaire   +3 more sources

Sustained release of sulphadiazine

Journal of Pharmacy and Pharmacology, 1978
Abstract An implantable system was developed which released sulphadiazine in mice over an extended period of time efficacious against infective challenges by Plasmodium berghei. The most successful preparation was a copolymer of L(+)-lactic acid + (±)-lactic acid (90 and 10% by weight, respectively) with a molecular weight of 150 000 ...
D L, Wise, G J, McCormick, G P, Willet, L C, Anderson, J F, Howes   +4 more
openaire   +2 more sources

Surface modification of pure titanium to improve its anti-inflammatory function

European Journal of Inflammation, 2015
Objective: Surface-modified titanium material was prepared to explore its corrosion resistance and microbial adhesion. Methods: Atmospheric pressure plasma was used to modify the surface of pure titanium. The surface morphology and adhesion morphology of
Hanwen Sun, Yancong Zhang, Linbo Dou, Xinfeng Song, Chunyan Sun   +4 more
doaj   +1 more source

Biphasic Drug Release from Rolled-Up Gelatin Capsules with a Cylindrical Cavity

Pharmaceutics, 2021
Biphasic drug delivery systems are used for quick release of a specific amount of drug for immediate amelioration of a patient’s state, followed by sustained release, to avoid repeated administration.
Jihane Mzoughi, Thierry Vandamme, Valeriy Luchnikov   +2 more
doaj   +1 more source

Prospective Survey on Safety Evaluation of Injectable Methylxanthines in Japan

Allergology International, 2006
Background: Injectable methylxanthines are useful drugs in the treatment of asthma. The Asthma Prevention and Management Guidelines (JGL) that are followed in Japan recommend the use of sustained-release theophylline to control the disease and use of ...
Ken Ohta, Sohei Makino, Mitsuru Adachi, Norio Kihara, Sigenori Nakajima, Sankei Nishima, Takeshi Fukuda, Terumasa Miyamoto   +7 more
doaj   +1 more source

Progress in the application of sustained-release drug microspheres in tissue engineering

Materials Today Bio, 2022
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with targeted and other effects. There are many types of sustained-release drug microspheres and various preparation methods, and they are easy to operate.
Lian Ruan, Mengrong Su, Xinyun Qin, Qingting Ruan, Wen Lang, Minhui Wu, Yujie Chen, Qizhuang Lv   +7 more
doaj   +1 more source

Sustained-release naltrexone for opioid dependence. [PDF]

Cochrane Database Syst Rev
Opioid dependence is a severe and often lifelong disorder with a high risk of overdose and premature death, as well as severe psychosocial difficulties. Sustained-release naltrexone is a treatment option that works by blocking the euphoric and overdose effects of opioids.
Kornør H, Lobmaier PPK, Kunøe N.
europepmc   +4 more sources

ROS-responsive tegafur-pheophorbide a conjugate-loaded microneedles for deep drug delivery and chemo-photodynamic therapy of superficial tumors

International Journal of Pharmaceutics: X
Superficial tumors, including breast cancer, melanoma, and oral carcinoma, pose significant treatment challenges due to their anatomical location and the inherent limitations of conventional therapies, such as systemic toxicity and poor tumor specificity.
Anning Li, Yingjie Ma, Yunfeng Dai, Yibin Guo, Yanjun He, Sihan Chen, Xinjie Su, Chenxi Fang, Long Chen, Meitao Duan, Ming Chen, Jungang Ren, Li Wang, Chen Wang, Zhiqiang Zhang   +14 more
doaj   +1 more source