Results 31 to 40 of about 2,524,657 (288)

An investigation into the use of metal nanoparticles and their oxides as antimicrobial agents [PDF]

, 2011
PhDNanotechnology is concerned with the study of processes and applications at the nanoscale (10-9 m), with objects that are generally smaller than 100 nm.
Vargas Reus, Miguel A.
core   +4 more sources

Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model [PDF]

, 2012
Background: The blood-brain barrier (BBB) represents an insurmountable obstacle for most drugs thus obstructing an effective treatment of many brain diseases.
Tikva Vogel, Zensi, Anja, von Briesen Hagen, Kreuter Jörg, Worek Franz, Tschickardt, Sabrina E., Sascha L Wien, Jörg Kreuter, Wien Sascha L., Vogel Tikva, Sabrina E Tschickardt, Wladislaw Maier, Vogel, Tikva, Sylvia Wagner, Claus U Pietrzik, Maier Wladislaw, Zensi Anja, Wien, Sascha L., Maier, Wladislaw, Tschickardt Sabrina E., Wagner, Sylvia, Pietrzik Claus U., Anja Zensi, Kreuter, Jörg, Worek, Franz, Hagen von Briesen, Pietrzik, Claus Ulrich, Briesen, Hagen von, Wagner Sylvia, Franz Worek   +29 more
core   +2 more sources

Effects of Particle Hydrophobicity, Surface Charge, Media pH Value and Complexation with Human Serum Albumin on Drug Release Behavior of Mitoxantrone-Loaded Pullulan Nanoparticles

Nanomaterials, 2015
We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per ...
Xiaojun Tao, Shu Jin, Dehong Wu, Kai Ling, Liming Yuan, Pingfa Lin, Yongchao Xie, Xiaoping Yang   +7 more
doaj   +1 more source

Optimization of Nanoparticles for Smart Drug Delivery: A Review

Nanomaterials, 2021
Nanoparticle delivery systems have good application prospects in the treatment of various diseases, especially in cancer treatment. The effect of drug delivery is regulated by the properties of nanoparticles.
Lina Jia, Peng Zhang, Hongyan Sun, Yuguo Dai, Shuzhang Liang, Xue Bai, Lin Feng   +6 more
doaj   +1 more source

Biosynthesis of core- shell ferrite-gold nanoparticles using Mentha aquatic plant extract and its application for 6-mercaptopurine drug delivery [PDF]

شیمی کاربردی روز, 2020
In this research work, core- shell ferrite-gold nanoparticles were synthesized by biosynthesis in two steps. In the first step, iron oxide nanoparticles were synthesized by biosynthesis using Mentha aquatic plant extract.
sadegh salmanpour, Mohammad Ali Khalilzadeh, Daryoush Zareyee, Hassan Karimi-Maleh   +3 more
doaj   +1 more source

Efficient chemotherapy of rat glioblastoma using Doxorubicin-loaded PLGA nanoparticles with different stabilizers [PDF]

, 2011
Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain.
Markus Glatzel, Kreuter, Jörg (Prof. Dr.), Christian Bernreuther, Olga Maksimenko, Maksimenko, Olga, Khalansky, Alexander S., Jörg Kreuter, Wohlfart, Stefanie, Gelperina, Svetlana, Svetlana Gelperina, Bernreuther, Christian, Stefanie Wohlfart, Alexander S Khalansky, Glatzel, Markus, Alexander S. Khalansky   +14 more
core   +2 more sources

Data-driven modeling of supercritical CO₂ processing with optimized machine learning: prediction of clobetasol propionate solubility

Frontiers in Medicine
Machine learning can be used to support data-driven modeling of supercritical CO₂ processing. The method of machine learning modeling is applied in this work for evaluation of small-molecule processing under supercritical conditions. As a necessary step,
Nidal H. Abu-Hamdeh, Mohammed N. Ajour
doaj   +1 more source

Construction of AC/DC magnetic syringe device for stimulated drug release, injection and ejection of nanocarriers and testing cytotoxicity in vitro

MethodsX, 2021
Iron nanoparticles are used as a targeted drug delivery system. The nanocarrier itself can be genotoxic, trigger oxidative stress or cell death. Therefore, we developed an AC/DC magnetic syringe for injecting, stimulating drug release and safe removing ...
Milorad Zjalić, Mislav Mustapić, Zvonko Glumac, Ivan Prološčić, Senka Blažetić, Ana Vuković, Mostafa Masud, Motasim Billah, Aslam Khan, Suzana Šegota, Md Shahriar Al Hossain, Marija Heffer   +11 more
doaj   +1 more source

Nanoparticles for antiparasitic drug delivery [PDF]

Drug Delivery, 2019
As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body.
Yuzhu Sun, Dongmei Chen, Yuanhu Pan, Wei Qu, Haihong Hao, Xu Wang, Zhenli Liu, Shuyu Xie   +7 more
openaire   +3 more sources

Development of High‐Drug‐Loading Nanoparticles [PDF]

ChemPlusChem, 2020
AbstractFormulating drugs into nanoparticles offers many attractive advantages over free drugs including improved bioavailability, minimized toxic side effects, enhanced drug delivery, feasibility of incorporating other functions such as controlled release, imaging agents for imaging, targeting delivery, and loading more than one drug for combination ...
Yun Liu, Guangze Yang, Song Jin, Letao Xu, Chun‐Xia Zhao   +4 more
openaire   +5 more sources