Results 281 to 290 of about 57,794 (383)

Diets Formulation and Weighted Gene Co-expression Network Analysis (WGCNA) Results

Xiaobei Li, RAMI AL BATRAN
openalex   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

SiCmiR Atlas: Single‐Cell miRNA Landscape Reveals Hub‐miRNA and Network Signatures in Human Cancers

Advanced Science, Volume 13, Issue 16, 18 March 2026.
SiCmiR predicts mature miRNA activity at single‐cell resolution using only 977 landmark genes, enabling scalable reconstruction of miRNA landscapes across diverse tissues and disease contexts. The SiCmiR Atlas integrates 9.36 million cells with analytical tools for hub‐miRNA discovery, biomarker prioritization, and regulatory network interrogation ...
Xiao‐Xuan Cai, Jing‐Shan Liao, Jia‐Jun Ma, Yu‐Xuan Pang, Yi‐Gang Chen, Yang‐Chi‐Dung Lin, Yi‐Dan Chen, Xin Cao, Yi‐Cheng Zhang, Tao‐Sheng Xu, Tzong‐Yi Lee, Hsi‐Yuan Huang, Hsien‐Da Huang   +12 more
wiley   +1 more source

Differential physiological responses and transcriptome co-expression networks of salt-tolerant and salt-sensitive foxtail millet (<i>Setaria italica</i> (L.)) under salt stress. [PDF]

Front Plant Sci
Liu M, Wang ZW, Hou S, Tian RM, Xie K, Bai J, Cong YZ, Yang Y, Liu W.   +8 more
europepmc   +1 more source

Identification of maize flowering gene co-expression modules by WGCNA

Acta Agronomica Sinica, 2019
Yu-Xin YANG, Zhi-Qin SANG, Cheng XU, Wen-Shuang DAI, Cheng ZOU   +4 more
openaire   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, Volume 13, Issue 17, 23 March 2026.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source

Immunotherapy impact of macrophage glycosylation on cholangiocarcinoma and its prognostic and immune microenvironment significance. [PDF]

Hum Vaccin Immunother
Xu Y, Xu X, Xu Y, Duan J.
europepmc   +1 more source

Identification and Validation of cGAS‐STING Pathway‐Associated Predictive and Therapeutic Models for Esophageal Squamous Cell Cancer Patients via Artificial Intelligence and Multi‐Omics

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Esophageal squamous cell cancer (ESCC) is a malignancy derived from the Esophagus, and dysregulation of the cGAS‐STING pathway contributes to ESCC progression. Method ESCC bulk‐seq dataset GSE38129 was acquired from GEO database and then underwent Limma and WGCNA analysis for the identification of shared DEGs, which were intersected
Chunyang Zhou, Xiaoli Liu, Zijian Wang, Tao Yang   +3 more
wiley   +1 more source

Artificial intelligence and multi-omics nominate TAZ as an insomnia-related diagnostic and druggable target for Parkinson's disease patients. [PDF]

Front Aging Neurosci
Ma W.
europepmc   +1 more source

Mechanistic role of GNE‐987 targeting BRD4‐HCP5 axis in pediatric T‐cell acute lymphoblastic leukemia

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang, Mengying Jiang, Yanchun Guan, Xin Chen, Zhen Zhang, Yumeng Wu, Wansheng Peng   +6 more
wiley   +1 more source