Results 241 to 250 of about 89,794 (315)

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

Targeted long-read genomic and epigenomic profiling enhances timely comprehensive variant discovery in hypotonia and muscle weakness. [PDF]

BMC Med
Abuijlan E, Sinha S, Ramaswamy S, Jain R, Chekroun I, Rabea F, El Naofal M, Khadija S, Sharaf R, Alkhnbashi OS, Ali F, Alsheikh-Ali A, Abou Tayoun A.   +12 more
europepmc   +1 more source

Spatial Regulation of Silicon Accumulation in Peduncle Confers Sheathed Spike in Barley

Plant Biotechnology Journal, EarlyView.
ABSTRACT Peduncle, the uppermost internode in cereals, connects the stem to the inflorescence and is critical for the transport of water, nutrients and photosynthetic assimilates. While peduncle length associates with plant height and its elongation is primarily regulated by phytohormones, we report a previously unrecognized mechanism involving the ...
Wenxue Wu, Congcong Jiang, Guangqi Gao, Namiki Mitani‐Ueno, Yu Guo, Jinhong Kan, Yehui Xiong, Martin Mascher, Zhongfu Ni, Jian Feng Ma, Ke Wang, Ping Yang   +11 more
wiley   +1 more source

Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.)

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng, Feiyan Qi, Lei Shi, Ziqi Sun, Hongfei Liu, Hua Liu, Li Qin, Juan Wang, Chenyang Zhi, Mengmeng Wang, Ziqiang Mo, Stefano Pavan, Xiao Wang, Yaojun Hu, Huanhuan Zhao, Xiaona Li, Wenzhao Dong, Meng Zhang, XiaoDong Dai, Zheng Zheng, Xinyou Zhang   +20 more
wiley   +1 more source

The DNA virome varies with human genes and environments. [PDF]

Nature
Kamitaki N, Tang D, McCarroll SA, Loh PR.   +3 more
europepmc   +1 more source

The effects of far‐UVC irradiation on the presence and concentration of ESKAPEE pathogens on hospital surfaces: Study protocol for a multi‐site, double‐blinded randomized controlled trial in La Paz, Bolivia

Photochemistry and Photobiology, EarlyView.
The protocol of a multi‐site, double‐blinded, clustered randomized controlled trial (cRCT) with a binary outcome of the presence of viable presumptive ESKAPEE pathogens on surfaces in and around hospital sinks is to be implemented in two Bolivian hospitals.
Lindsay B. Saber, Melani Rojas, Darcy M. Anderson, Deverick J. Anderson, Holger Claus, Ryan Cronk, Karl G. Linden, Megan E. J. Lott, Lewis J. Radonovich Jr., Bobby G. Warren, Richard D. Williamson, Richard L. Vincent, Sergio Gutiérrez‐Cortez, Carla Calderón Toledo, Joe Brown   +14 more
wiley   +1 more source

A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti. [PDF]

Parasit Vectors
Daron J, Lecuyer A, Ma L, Marzooghi P, Breban MI, Kyrylos P, Donovan-Banfield I, Redmond SN, Lambrechts L.   +8 more
europepmc   +1 more source

Entwicklungsstand der LMÜ-WGS Plattform GenÜSBa v2.0 - Rollen & Rechte Konzept

Hauck, Hanna, Zerndt, Arndt, Brendebach, Holger   +2 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

A comparative review of three cloud-based platforms for microbial whole genome sequencing analysis. [PDF]

Antimicrob Steward Healthc Epidemiol
Hwang M, Choi H, Chatterjee P, Jinadatha C.   +3 more
europepmc   +1 more source