Results 51 to 60 of about 174,007 (375)

Implementing Whole Genome Sequencing (WGS) in Clinical Practice: Advantages, Challenges, and Future Perspectives

Cells
The integration of whole genome sequencing (WGS) into all aspects of modern medicine represents the next step in the evolution of healthcare. Using this technology, scientists and physicians can observe the entire human genome comprehensively, generating
P. Brlek, Luka Bulić, Matea Bračić, Petar Projić, V. Škaro, Nidhi Shah, Parth Shah, D. Primorac   +7 more
semanticscholar   +1 more source

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

European Journal of Human Genetics, 2017
Genetic imputation is a cost-efficient way to improve the power and resolution of genome-wide association (GWA) studies. Current publicly accessible imputation reference panels accurately predict genotypes for common variants with minor allele frequency (
M. Mitt, M. Kals, K. Pärn, S. Gabriel, E. Lander, A. Palotie, S. Ripatti, A. Morris, A. Metspalu, T. Esko, R. Mägi, P. Palta   +11 more
semanticscholar   +1 more source

Cr-Free, Cu Promoted Fe Oxide-Based Catalysts for High-Temperature Water-Gas Shift (HT-WGS) Reaction

Catalysts, 2020
Ca, Ni, Co, and Ge promoters were examined as potential candidates to substitute for the current toxic Cr in Cu-promoted Fe oxide-based catalysts for the HT-WGS reaction.
S. Sourav, I. Wachs
semanticscholar   +1 more source

The Resistance and Virulence Characteristics of Salmonella Enteritidis Strain Isolated from Patients with Food Poisoning Based on the Whole-Genome Sequencing and Quantitative Proteomic Analysis

Infection and Drug Resistance, 2023
Benjin Xu,1– 3,* Zhuru Hou,2,4,* Ling Liu,1– 3,* Rongrong Yan,3 Jinjing Zhang,3 Jianhong Wei,4 Miao Du,1,2 Yan Xuan,1,2 Lei Fan,2,4 Zhuoxi Li2,4 1Department of Medical Laboratory Science, Fenyang College of Shanxi Medical University, Fenyang,
Xu B, Hou Z, Liu L, Yan R, Zhang J, Wei J, Du M, Xuan Y, Fan L, Li Z   +9 more
doaj  

Contour and Digital Terrain Models of Soil Properties Digital Maps Using Geographic Information System [PDF]

Engineering and Technology Journal, 2010
The research aims to use the technical abilities for geographic information system in the field of designing and drawing maps by saving huge amount of information in a fast and organized way also to shows data and maps from the computer in high speed. In
doaj   +1 more source

Characterizing sensitivity and coverage of clinical WGS as a diagnostic test for genetic disorders

bioRxiv, 2020
Background Due to its reduced cost and incomparable advantages, WGS is likely to lead to changes in clinical diagnosis of rare and undiagnosed diseases.
Yan Sun, Fengxia Liu, C. Fan, Yaoshen Wang, Lijie Song, Zhonghai Fang, R. Han, Zhonghua Wang, Xiaodan Wang, Ziying Yang, Zhenpeng Xu, Jiguang Peng, C. Shi, Hongyun Zhang, W. Dong, Hui Huang, Yun Li, Yanqun Le, Jun Sun, Zhiyu Peng   +19 more
semanticscholar   +1 more source

Discovery and genotyping of structural variation from long-read haploid genome sequence data [PDF]

, 2016
In an effort to more fully understand the full spectrum of human genetic variation, we generated deep single-molecule, real-time (SMRT) sequencing data from two haploid human genomes.
Boitano, Matthew, Chaisson, Mark J.P., Chin, Chen-Shin, Eichler, Evan E, Gordon, David, Graves-Lindsay, Tina A, Hoekzema, Kendra, Huddleston, John, Korlach, Jonas, Kronenberg, Zev N, Munson, Katherine M, Peluso, Paul, Steinberg, Karyn Meltz, Vives, Laura, Warren, Wes, Wilson, Richard K   +15 more
core   +2 more sources

WGS to predict antibiotic MICs for Neisseria gonorrhoeae

Journal of Antimicrobial Chemotherapy, 2017
Background Tracking the spread of antimicrobial-resistant Neisseria gonorrhoeae is a major priority for national surveillance programmes. Objectives We investigate whether WGS and simultaneous analysis of multiple resistance determinants can be used to ...
D. Eyre, Dilrini De Silva, K. Cole, Joanna Peters, M. Cole, Y. Grad, W. Demczuk, I. Martin, M. Mulvey, D. Crook, A. Walker, T. Peto, J. Paul   +12 more
semanticscholar   +1 more source

Whole genome sequencing and microsatellite analysis of the Plasmodium falciparum E5 NF54 strain show that the var, rifin and stevor gene families follow Mendelian inheritance [PDF]

, 2018
Background: Plasmodium falciparum exhibits a high degree of inter-isolate genetic diversity in its variant surface antigen (VSA) families: P. falciparum erythrocyte membrane protein 1, repetitive interspersed family (RIFIN) and subtelomeric variable ...
Bruske, Ellen, Frank, Matthias, Otto, Thomas D.   +2 more
core   +5 more sources

Towards standardisation: comparison of five whole genome sequencing (WGS) analysis pipelines for detection of epidemiologically linked tuberculosis cases

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019
Background Whole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.
R. Jajou, T. Kohl, T. Walker, A. Norman, D. Cirillo, E. Tagliani, S. Niemann, A. D. de Neeling, T. Lillebaek, R. Anthony, D. van Soolingen   +10 more
semanticscholar   +1 more source