Results 71 to 80 of about 98,982 (312)

CARACTERIZACIÓN Y EVALUACIÓN DE CATALIZADORES DE NÍQUEL EN LA REACCIÓN WGS

Revista de Investigaciones Universidad del Quindío, 2013
La producción de hidrogeno es de vital importancia para diversos procesos industriales y en este contexto la reacción WGS es de gran utilidad para conseguir altos valores de pureza de este elemento, especialmente por su reciente uso en la obtención de ...
Maria do Carmo Rangel, Johana Rodriguez Ruiz, Edgardo Meza Fuentes   +2 more
doaj  

Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment

Advanced Science, EarlyView.
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo, Yijuan Wang, Dengwang Chen, Yinghan Zhang, Yi Shuai, Hualiang Yao, Tao Jiang, Hang Jiang, Ming Zhong, Xiangeng Wang, Ziwei Wang, Chenchen Xu, Ajay Goel, Hoi Tang MA, Feng Gao, Xin Wang   +15 more
wiley   +1 more source

Antimicrobial Resistance and the Genomic Epidemiology of Multidrug-Resistant Salmonella enterica serovar Enteritidis ST11 in China

Frontiers in Bioscience-Landmark
Background: With the recent evolution of multidrug-resistant strains, the genetic characteristics of foodborne Salmonella enterica serovar Enteritidis and clinical isolates have changed. ST11 is now the most common genotype associated with S. Enteritidis
Jie Liu, Yue Hou, Linna Zhao, Gang Chen, Jialiang Chen, Qiang Zhao, Liyan Ye, Shenghui Cui, Chengbin Wang   +8 more
doaj   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Genetic characterisation of Germanata Veneta and Mignon local duck breeds (Anas platyrhynchos) using whole-genome sequencing

Italian Journal of Animal Science
This study investigated the genetic diversity and conservation status of two endangered Italian duck breeds: Germanata Veneta (GER, n = 50) and Mignon (MIG, n = 50). The DNA was extracted from blood and analysed through whole-genome sequencing.
Francesco Perini, Enrico Bortoletto, Filippo Cendron, Umberto Rosani, Emiliano Lasagna, Maristella Baruchello, Martino Cassandro, Mauro Penasa   +7 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

WGS and RNAseq metrics.

, 2012
WGS and RNAseq metrics.
Haiyong Han (128169), Glen J. Weiss (128085), Angela Baker (128155), Rafael Fonseca (128188), Jeffrey A. Kiefer (128138), Michael J. Demeure (128078), Galen H. Hostetter (128150), Esteban Braggio (128134), Richard Posner (128144), Douglas Lake (128175), Michael Barrett (128123), Hollie Benson (128130), A. Keith Stewart (128191), Jessica Aldrich (128110), Waibhav Tembe (117037), Mitesh J. Borad (128074), Jan B. Egan (128161), Daniel Von Hoff (117063), Tyler Izatt (128091), Ahmet Kurdoglu (128116), Shripad Sinari (128099), David W. Craig (128068), Christophe Legendre (117048), Ramesh K. Ramanathan (128184), Edward C. Stites (128180), Winnie S. Liang (105564), Alexis Christoforides (128104), Lori Phillips (128126), John Carpten (117061)   +28 more
core   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Validated MP-WGS findings.

, 2018
Validated MP-WGS findings.
Anh Nhi Tran (4952269), Magnus Nordenskjöld (118610), Daniel Nilsson (29307), Francesco Vezzi (107361), Ingegerd Ivanov Öfverholm (4952275), Britta Lötstedt (3552956), Vasilios Zachariadis (4952278), Ann Nordgren (507950), Gisela Barbany (4952266), Fulya Taylan (4952272), Anna Lindstrand (764128)   +10 more
core   +1 more source