Results 51 to 60 of about 3,973 (202)

Population genomics of ancient and modern Trichuris trichiura

Nature Communications, 2022
The whipworm Trichuris trichiura is a soil-transmitted helminth that causes the neglected tropical disease trichuriasis in humans. Here, the authors produce whole genome sequences of modern and ancient samples from humans and non-human primates to ...
Stephen R. Doyle, Martin Jensen Søe, Peter Nejsum, Martha Betson, Philip J. Cooper, Lifei Peng, Xing-Quan Zhu, Ana Sanchez, Gabriela Matamoros, Gustavo Adolfo Fontecha Sandoval, Cristina Cutillas, Louis-Albert Tchuem Tchuenté, Zeleke Mekonnen, Shaali M. Ame, Harriet Namwanje, Bruno Levecke, Matthew Berriman, Brian Lund Fredensborg, Christian Moliin Outzen Kapel   +18 more
doaj   +1 more source

Mitogenomics and Evolutionary History of Rodent Whipworms (Trichuris spp.) Originating from Three Biogeographic Regions

Life, 2021
Trichuris spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (Trichuris ...
Jan Petružela, Alexis Ribas, Joëlle Goüy de Bellocq   +2 more
doaj   +1 more source

Trichuris trichiura in a post-Colonial Brazilian mummy

Memorias do Instituto Oswaldo Cruz, 2015
Trichuris trichiura is a soil-transmitted helminth which is prevalent in warm, moist, tropical and subtropical regions of the world with poor sanitation. Heavy whipworm can result either in Trichuris dysenteric syndrome - especially in children - or in a
Rafaella Bianucci, Eduardo J Lopes Torres, Juliana MF Dutra Santiago, Luis F Ferreira, Andreas G Nerlich, Sheila Maria Mendonça de Souza, Valentina Giuffra, Pedro Paulo Chieffi, Otilio Maria Bastos, Renata Travassos, Wanderley de Souza, Adauto Araújo   +11 more
doaj   +1 more source

Characterization of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host–parasite communication

Journal of Extracellular Vesicles, 2018
Whipworms are parasitic nematodes that live in the gut of more than 500 million people worldwide. Owing to the difficulty in obtaining parasite material, the mouse whipworm Trichuris muris has been extensively used as a model to study human whipworm ...
Ramon M. Eichenberger, Md Hasanuzzaman Talukder, Matthew A. Field, Phurpa Wangchuk, Paul Giacomin, Alex Loukas, Javier Sotillo   +6 more
doaj   +1 more source

Mitochondrial and nuclear ribosomal DNA evidence supports the existence of a new Trichuris species in the endangered françois' leaf-monkey. [PDF]

PLoS ONE, 2013
The whipworm of humans, Trichuris trichiura, is responsible for a neglected tropical disease (NTD) of major importance in tropical and subtropical countries of the world.
Guo-Hua Liu, Robin B Gasser, Peter Nejsum, Yan Wang, Qiang Chen, Hui-Qun Song, Xing-Quan Zhu   +6 more
doaj   +1 more source

High prevalence of Clonorchis sinensis infection in Guangxi, Southern China

Tropical Medicine and Health, 2021
Background Soil-transmitted helminths (STHs), such as hookworm, roundworm and whipworm, and food-borne trematodiases, including Clonorchis sinensis, remain a public health problem worldwide, especially in tropical and subtropical regions.
Zhi-Hua Jiang, Xiao-Ling Wan, Guo-Li Lv, Wei-Wei Zhang, Yuan Lin, Wen-Qian Tang, Hai-Yan Wei, Fang-Qi Ou, Yun-Liang Shi, Yi-Chao Yang, Jian Liu, Carlos H. F. Chan   +11 more
doaj   +1 more source

Trichuris trichiura (Linnaeus, 1771) From Human and Non-human Primates: Morphology, Biometry, Host Specificity, Molecular Characterization, and Phylogeny

Frontiers in Veterinary Science, 2021
Human trichuriasis is a Neglected Tropical Disease, which affects hundreds of millions of persons worldwide. Several studies have reported that non-human primates (NHP) represent important reservoirs for several known zoonotic infectious diseases.
Julia Rivero, Cristina Cutillas, Rocío Callejón   +2 more
doaj   +1 more source

Functional Characterization of the Oxantel-Sensitive Acetylcholine Receptor from Trichuris muris

Pharmaceuticals, 2021
The human whipworm, Trichuris trichiura, is estimated to infect 289.6 million people globally. Control of human trichuriasis is a particular challenge, as most anthelmintics have a limited single-dose efficacy, with the striking exception of the narrow ...
Tina V. A. Hansen, Richard K. Grencis, Mohamed Issouf, Cédric Neveu, Claude L. Charvet   +4 more
doaj   +1 more source

Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction [PDF]

, 2014
Whipworms are common soil-transmitted helminths that cause debilitating chronic infections in man. These nematodes are only distantly related to Caenorhabditis elegans and have evolved to occupy an unusual niche, tunneling through epithelial cells of the
Berriman, M, Allison J Bancroft, Jimmy Z Liu, Cooper, Philip J, Sarah Nichol, Grencis, RK, Nancy Holroyd, Foth, Bernardo J., Berriman, Matthew, Alan Tracey, Zarowiecki, M, Cotton, James A., Bancroft, Allison J., Holroyd, N, Liu, Jimmy Z, Grencis, Richard K., Bancroft, Allison J, Cotton, James A, Eleanor J Stanley, Bancroft, AJ, Foth, Bernardo J, Reid, Adam J, Tracey, Alan, Tsai, IJ, Holroyd, Nancy, Richard K Grencis, Liu, JZ, Huckvale, T, Zarowiecki, Magdalena, Cooper, PJ, Cooper, Philip, Tsai, Isheng J., Reid, Adam J., Stanley, Eleanor J, Huckvale, Thomas, Adam J Reid, Cotton, JA, Grencis, Richard K, Nichol, Sarah, Stanley, Eleanor J., Stanley, EJ, James A Cotton, Thomas Huckvale, Magdalena Zarowiecki, Nichol, S, Tsai, Isheng J, Cooper, Philip J., Reid, AJ, Liu, Jimmy Z., Tracey, A, Bernardo J Foth, Philip J Cooper, Matthew Berriman, Isheng J Tsai, Foth, BJ   +54 more
core   +2 more sources

New evidence for the antiquity of the intestinal parasiteTrichuris(whipworm) in Europe

, 2004
The whipworm,Trichuris trichiuraL., is one of the most common human intestinal parasites worldwide, yet little is known of its origin and global spread.
Petra Dark
core   +1 more source