Dysbiosis and Therapeutic Modulation of the Gut Microbiota in Multiple Sclerosis: A Narrative Review
ABSTRACT Background and Aims Multiple sclerosis (MS) is a persistent autoimmune disease that affects the central nervous system. The etiology of MS is complex, involving a variety of genetic and environmental factors. Mounting evidence suggests that dysbiosis significantly impacts the progression of MS mainly through its direct effects upon the immune ...
Mojtaba Memariani, Hamed Memariani
wiley +1 more source
Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction [PDF]
Whipworms are common soil-transmitted helminths that cause debilitating chronic infections in man. These nematodes are only distantly related to Caenorhabditis elegans and have evolved to occupy an unusual niche, tunneling through epithelial cells of the
Berriman, M +54 more
core +2 more sources
Colonoscopic Diagnosis of Trichuris Trichiura In A Patient With Pulmonary Tuberculosis
Trichuris trichiura is a soil-transmitted intestinal helminth infection. Although mild cases are asymptomatic, heavy whipworm burdens lead to colitis with chronic abdominal pain, diarrhea, dysentery, anemia, and rectal prolapse.
Huzaifah Salat +3 more
doaj
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley +1 more source
Seasonality and changing prevalence of common canine gastrointestinal nematodes in the USA
Background The three most commonly diagnosed gastrointestinal parasites of pet dogs within the USA are the whipworm, the hookworm, and the roundworm. The collection of large data sets from various sources throughout the industry have produced a number of
Jason Drake, Tom Carey
doaj +1 more source
Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou +7 more
wiley +1 more source
Abstract An 8‐year‐4‐month‐old, female, neutered labrador retriever with acute haemorrhagic diarrhoea was unresponsive to symptomatic and antibiotic treatment, and developed gastrointestinal protein loss leading to significant hypoalbuminaemia.
Luis Miguel Garcia Roldan +3 more
wiley +1 more source
Human Trichuriasis: Whipworm Genetics, Phylogeny, Transmission and Future Research Directions [PDF]
Human trichuriasis is a neglected tropical disease which affects hundreds of millions of people worldwide and is particularly prevalent among children living in areas where sanitation is poor.
Betson, Martha +2 more
core +1 more source
A genetic analysis of Trichuris trichiura and Trichuris suis from Ecuador
Background Since the nematodes Trichuris trichiura and T. suis are morphologically indistinguishable, genetic analysis is required to assess epidemiological cross-over between people and pigs.
Hayley Meekums +9 more
doaj +1 more source
New Perspectives on Classical Alarmin Responses to Intestinal Helminth Infection
ABSTRACT Interleukins 33, 25, and thymic stromal lymphopoietin (TSLP) are core components of type two immune responses and have been studied extensively using helminth infection models. However, many questions remain regarding their cellular sources, their immune recipients, as well as how they shape immunity.
Connor P. Lynch, Richard K. Grencis
wiley +1 more source

