Results 51 to 60 of about 10,512,321 (293)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
International Journal of General Medicine, 2021 Xiao Li,1,* Zicheng Xu,1,* Ting Xu,1,* Feng Qi,1 Ninghong Song2 1Department of Urology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210009, People’s ...
Li X, Xu Z, Xu T, Qi F, Song N
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A population synthesis study of the luminosity function of hot white dwarfs
, 2014 We present a coherent and detailed Monte Carlo simulation of the population of hot white dwarfs. We assess the statistical significance of the hot end of the white dwarf luminosity function and the role played by the bolometric corrections of hydrogen ...
García-Berro, E. +3 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Otolaryngologic Clinics of North America, 2011 Increased thickness of the epithelium imparts a white appearance to the oral mucosa by increasing the distance to the underlying blood vessels. Usually this thickening is a result of the increased formation of keratin. Some other less common causes of white lesions are acanthosis or a thickening of the spinous cell layer, edema of the epithelium, or ...
Department of Oral and Maxillofacial Diagnostic Sciences, Oral +3 more
openaire +3 more sources
Crowdsourcing the Worlds, Blog 9 [PDF]
, 2015 Student blog posts from the Great VCU Bike Race ...
White, Niyah
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Embedding realistic surveys in simulations through volume remapping
, 2010 Connecting cosmological simulations to real-world observational programs is often complicated by a mismatch in geometry: while surveys often cover highly irregular cosmological volumes, simulations are customarily performed in a periodic cube.
Fullana +4 more
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source