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White matter ischaemia

Brain Research Reviews, 1999
Brain and spinal cord white matter are vulnerable to the effects of ischaemia. Reduction of the energy supply leads to a cascade of events including depolarization, influx of Na(+) and the subsequent reverse operation of the membrane protein the Na(+)/Ca(2+) exchanger which ultimately terminates in intracellular Ca(2+) overload and irreversible axonal ...
M A, Petty, J G, Wettstein
openaire   +2 more sources

Impact of white matter hyperintensities on surrounding white matter tracts

Neuroradiology, 2018
It is unclear how white matter hyperintensities disrupt surrounding white matter tracts. The aim of this tractography study was to determine the spatial relationship between diffusion characteristics along white matter tracts and the distance from white matter hyperintensities.Diffusion tensor 3-T MRI scans were acquired in 29 participants with white ...
William Reginold   +5 more
openaire   +2 more sources

White matter lactate – Does it matter?

Neuroscience, 2014
About half of the human brain is white matter, characterized by axons covered in myelin, which facilitates the high speed of nerve signals from one brain area to another. At the time of myelination, the oligodendrocytes that synthesize myelin require a large amount of energy for this task.
Rinholm, J E, Bergersen, Linda Hildegard
openaire   +3 more sources

White Matter's the Matter

Science, 2003
Scientists have long known that connections somehow go awry in the brains of people with schizophrenia. Now advances in imaging and gene technology are allowing them to trace the axons that connect from neuron to neuron and make up the brain9s white matter.
openaire   +1 more source

White matter pathology in phenylketonuria☆

Molecular Genetics and Metabolism, 2010
Early-treated phenylketonuria (PKU) is associated with a range of neuropsychological impairments. Proposed mechanisms for these impairments include dopamine depletion and white matter pathology. Neuroimaging studies demonstrate high-signal intensity in the periventricular white matter in most PKU patients, which can extend into subcortical and frontal ...
P. J. Anderson, LEUZZI, Vincenzo
openaire   +3 more sources

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