Results 271 to 280 of about 3,224,961 (325)
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Brain Research Reviews, 1999
Brain and spinal cord white matter are vulnerable to the effects of ischaemia. Reduction of the energy supply leads to a cascade of events including depolarization, influx of Na(+) and the subsequent reverse operation of the membrane protein the Na(+)/Ca(2+) exchanger which ultimately terminates in intracellular Ca(2+) overload and irreversible axonal ...
M A, Petty, J G, Wettstein
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Brain and spinal cord white matter are vulnerable to the effects of ischaemia. Reduction of the energy supply leads to a cascade of events including depolarization, influx of Na(+) and the subsequent reverse operation of the membrane protein the Na(+)/Ca(2+) exchanger which ultimately terminates in intracellular Ca(2+) overload and irreversible axonal ...
M A, Petty, J G, Wettstein
openaire +2 more sources
"Vanishing white matter" (VWM) is a leukodystrophy caused by autosomal recessive pathogenic variants in the genes encoding the subunits of eukaryotic initiation factor 2B (eIF2B). Disease onset and disease course are extremely variable. Onset varies from the antenatal period until senescence. The age of onset is predictive of disease severity.
van der Knaap, Marjo S. +2 more
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van der Knaap, Marjo S. +2 more
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Current opinion in neurology and neurosurgery, 1991
Magnetic resonance imaging (MRI) has a leading role in the diagnosis of white matter disorders because of its superior sensitivity. It also allows a detailed analysis of white matter disorders, improving the specificity of the diagnoses. There is an increasing knowledge about MRI patterns, in particular in hereditary metabolic disorders.
Valk, J., Van der Knaap, M. S.
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Magnetic resonance imaging (MRI) has a leading role in the diagnosis of white matter disorders because of its superior sensitivity. It also allows a detailed analysis of white matter disorders, improving the specificity of the diagnoses. There is an increasing knowledge about MRI patterns, in particular in hereditary metabolic disorders.
Valk, J., Van der Knaap, M. S.
openaire +2 more sources
White matter lactate – Does it matter?
Neuroscience, 2014About half of the human brain is white matter, characterized by axons covered in myelin, which facilitates the high speed of nerve signals from one brain area to another. At the time of myelination, the oligodendrocytes that synthesize myelin require a large amount of energy for this task.
Rinholm, J E, Bergersen, Linda Hildegard
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American Journal of Psychiatry, 2007
The axonal membrane and the myelin sheets around axons restrict water diffusion perpendicular to the fiber orientation in white matter but not along the axon’s main axis, which leads to anisotropic diffusion of water. Over the last decade, the quantitative measurement of this anisotropy by using what has been called diffusion tensor imaging (DTI) has ...
Susumu, Mori, Peter, van Zijl
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The axonal membrane and the myelin sheets around axons restrict water diffusion perpendicular to the fiber orientation in white matter but not along the axon’s main axis, which leads to anisotropic diffusion of water. Over the last decade, the quantitative measurement of this anisotropy by using what has been called diffusion tensor imaging (DTI) has ...
Susumu, Mori, Peter, van Zijl
openaire +2 more sources

