Results 131 to 140 of about 143,855 (296)
Determinants of cerebral white matter lesions: A longitudinal population based MRI study [PDF]
, 1999 W hite matter lesions are frequently found on cerebral magnetic resonance imaging scans of elderly non-demented and demented people. l-4 The pathogenesis of white matter lesions is largely unknown.
de Leeuw, HF, Leeuw, H.F. (Frank) de
core +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
Advanced Functional Materials, EarlyView.This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Sea cucumber mutable collagenous tissue (MCT) is a remarkable collagen‐based material which can rapidly undergo large changes in stiffness through transiently bound effector proteins. Here, we investigate the hierarchical structure and mechanical response of MCT from Cucumaria frondosa across length scales with a wide range of methods, also exploring ...
Nathalie R. H. Singh +7 more
wiley +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
Advanced Healthcare Materials, EarlyView.An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Multiple Sclerosis–Specific Sign: Ependymal Dot–Dash Sign/Dawson Fingers/Central Vein Sign
Annals of Internal Medicine: Clinical CasesMultiple sclerosis is most common inflammatory-demyelinating disease of the central nervous system, affecting the brain and spinal cord. Magnetic resonance imaging is the primary technique for identifying white matter lesions as demyelinating lesions ...
Romeo Thierry Yehouenou Tessi +3 more
doaj +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Sutures are crucial for tissue approximation and wound healing. Besides their strength limits requirement, they often fail to effectively address complications like infection and pain. Inspired by natural silk's “core‐sheath” structure, our suture features a wet‐spun core of n zinc‐fortified silk fibroin fibers (RSF‐Zn2+) after drawing with ...
Yi Peng +11 more
wiley +1 more source
Potentiation of cortico-spinal output via targeted electrical stimulation of the motor thalamus
Nature CommunicationsCerebral white matter lesions prevent cortico-spinal descending inputs from effectively activating spinal motoneurons, leading to loss of motor control. However, in most cases, the damage to cortico-spinal axons is incomplete offering a potential target ...
Jonathan C. Ho +17 more
doaj +1 more source