Results 251 to 260 of about 143,855 (296)

Evolution of White Matter Lesions

Cerebrovascular Diseases, 2002
A 3-year follow-up of 273 participants (mean age 60 years) of the Austrian Stroke Prevention Study provides first information on the rate, clinical predictors and cognitive consequences of MRI white matter lesions (WML) in elderly individuals without neuropsychiatric disease.
Reinhold, Schmidt, Helena, Schmidt, Peter, Kapeller, Anita, Lechner, Franz, Fazekas   +4 more
openaire   +2 more sources

White matter lesion in the elderly

Journal of the Neurological Sciences, 1992
The advent of neuroimaging has brought medical attention to the frequency of unsuspected white matter lesions in the brains of elderly people. In 1987 Hachinski suggested the term "leuko-araiosis" to identify such white matter abnormalities detected by computed tomography and magnetic resonance imaging to emphasize that their etiology and clinical ...
J S, Meyer, J, Kawamura, Y, Terayama
openaire   +2 more sources

Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain [PDF]

Brain Pathology, 2015
White matter lesions (WML) are common in brain aging and are associated with dementia. We aimed to investigate whether oxidative DNA damage and occur in WML and in apparently normal white matter in cases with lesions.
Carol Brayne, Paul Ince, Fiona Matthews   +2 more
exaly   +3 more sources

Viral Infections and White Matter Lesions

Radiologic Clinics of North America, 2014
This article discusses imaging findings in virus-related infectious and noninfectious encephalitis/encephalopathy with white matter involvement, as well as the differential diagnosis based on the characteristic distribution. Acute viral encephalitis/encephalopathy is a medical emergency.
Toshio, Moritani, Aristides, Capizzano, Patricia, Kirby, Bruno, Policeni   +3 more
openaire   +2 more sources

Stuporous catatonia and white matter lesions

Journal of Clinical Neuroscience, 2009
A 42-year-old woman was taken to hospital with a 3-day history of progressive confusion and agitation. On observation, she was mute and displayed significant immobility. At times, the immobility was accompanied by catalepsy or ‘‘waxy flexibility”. There was no obvious evidence of focal neurological deficits.
James, Scozzafava, Yasser, Aladdin, Glen, Jickling, Negar, Asdaghi, Muhammad, Hussain, Fabrizio, Giuliani   +5 more
openaire   +2 more sources

CT and MRI Rating of White Matter Lesions

Cerebrovascular Diseases, 2002
Rating scales play an important role in the evaluation of computed tomography (CT) or magnetic resonance-detected white matter lesions (WML). Unfortunately, this type of visual semiquantitative assessment is not yet an optimal tool because commonly agreed concepts regarding its use are lacking.
Fazekas, Franz, Barkhof, F, Wahlund, L. O, PANTONI, LEONARDO, Erkinjuntti, T, Scheltens, P, SCHMIDT, REINHARD EDWIN   +6 more
openaire   +5 more sources

Genetic variation in homocysteine metabolism, cognition, and white matter lesions [PDF]

Neurobiology of Aging, 2010
Several studies have shown an association between homocysteine concentration and cognitive performance or cerebral white matter lesions. However, variations in genes encoding for enzymes and other proteins that play a role in homocysteine metabolism have
Monique M B Breteler, David Smith, André G Uitterlinden   +2 more
exaly   +2 more sources

Cognition and White Matter Lesions

Cerebrovascular Diseases, 2002
Although it is recognized that ischemic stroke is a potent risk factor for vascular dementia, the influence of white matter lesions (WML) on cognitive function is less clear. In community-based MRI studies that have administered mental status tests to subjects who were free of clinically evident neurologic disease, a weak relationship between WML and ...
openaire   +2 more sources

White matter lesions and cognition

Neurology, 2006
Neurologists and neuroradiologists often see small T2-hyperintense lesions in the hemispheric white matter of patients who undergo MR imaging. Such findings often lead to neurologic consultation, particularly when the reason for MR imaging was not to study the white matter.
Michael D. Hill, J. Ross Mitchell
openaire   +1 more source

Microglial activation in white matter lesions and nonlesional white matter of ageing brains

Neuropathology and Applied Neurobiology, 2007
White matter lesions (WML), a common feature in brain ageing, are classified as periventricular (PVL) or deep subcortical (DSCL), depending on their anatomical location. Microglial activation is implicated in a number of neurodegenerative diseases, but the microglial response in WML is poorly characterized and its role in pathogenesis unknown.
Simpson, J. E., Ince, P. G., Higham, C. E., Gelsthorpe, C. H., Fernando, M. S., Matthews, F., Forster, G., O'Brien, J. T., Barber, R., Kalaria, R. N., Brayne, C., Shaw, P. J., Stoeber, K., Williams, G. H., Lewis, C. E., Wharton, S. B.   +15 more
openaire   +3 more sources