Results 61 to 70 of about 13,623,762 (302)

Unmyelinated white matter loss in the preterm brain is associated with early increased levels of end-tidal carbon monoxide.

PLoS ONE, 2014
ObjectiveIncreased levels of end-tidal carbon monoxide (ETCOc) in preterm infants during the first day of life are associated with oxidative stress, inflammatory processes and adverse neurodevelopmental outcome at 2 years of age.
Cornelie A Blok, Karina J Kersbergen, Niek E van der Aa, Britt J van Kooij, Petronella Anbeek, Ivana Isgum, Linda S de Vries, Tannette G Krediet, Floris Groenendaal, Hendrik J Vreman, Frank van Bel, Manon J Benders   +11 more
doaj   +1 more source

White matter volume in alcohol use disorders: a meta‐analysis [PDF]

Addiction Biology, 2012
ABSTRACTAtrophy of brain white matter (WM) often is considered a signature injury of alcohol use disorders (AUDs). However, investigations into AUD‐related changes in WM volume have yielded complex findings that are difficult to synthesize in a narrative review.
Mollie A, Monnig, J Scott, Tonigan, Ronald A, Yeo, Robert J, Thoma, Barbara S, McCrady   +4 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Morphometric and microstructural characteristics of the brain in patients with temporal lobe epilepsy

Анналы клинической и экспериментальной неврологии
Introduction. The study of morphometric and microstructural characteristics of the brain in patients with temporal lobe epilepsy (TLE) represents one of the most rapidly advancing areas of neuroimaging research.
Marina Yu. Maximova, Anna D. Shitova, Marina V. Krotenkova, Anastasia N. Sergeeva   +3 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Equine Stereotaxtic Population Average Brain Atlas With Neuroanatomic Correlation

Frontiers in Neuroanatomy, 2019
There is growing interest in the horse for behavioral, neuroanatomic and neuroscientific research due to its large and complex brain, cognitive abilities and long lifespan making it neurologically interesting and a potential large animal model for ...
Philippa J. Johnson, Valentin Janvier, Wen-Ming Luh, Marnie FitzMaurice, Teresa Southard, Erica F. Barry   +5 more
doaj   +1 more source

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

NeuroImage: Clinical, 2023
Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their ...
Christine Kindler, Neeraj Upadhyay, Zeynep Bendella, Franziska Dorn, Vera C. Keil, Gabor C. Petzold   +5 more
doaj   +1 more source

Decline in intelligence is associated with progression in white matter hyperintensity volume [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2005
To quantify the time course of white matter hyperintensities (WMH) and assess the association between progression and cognitive decline in non-demented octogenarians.From a Danish cohort of 698 people born in 1914, 26 participated in neuropsychological assessment (Wechsler adult intelligence scale) initiated at age 50, including cognitive testing and ...
Garde, E, Mortensen, Erik Lykke, Rostrup, E, Paulson, O B   +3 more
openaire   +3 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source