Archiv der Pharmazie, Volume 359, Issue 2, February 2026.We identified a novel N9‐substituted harmine analog, compound 6, that selectively suppresses leukemic cell growth, triggers DNA damage, and activates apoptosis while sparing healthy fibroblasts. This discovery highlights N9‐modified β‐carbolines as a powerful new class of selective antileukemic agents, bridging natural product chemistry with next ...
Abdul Aziz Timbilla +17 more
wiley +1 more source
Conversion of Lignocellulosic Biomass Into Valuable Feed for Ruminants Using White Rot Fungi. [PDF]
J Anim Physiol Anim Nutr (Berl)Zheng C +4 more
europepmc +1 more source
Comparative Analysis of HEK293 Genomic Variability
Biotechnology and Bioengineering, Volume 123, Issue 2, Page 436-448, February 2026.An investigation of how HEK293‐derived cell lines adapt genetically to different culture conditions and environmental pressures: despite distinct phenotypes and cultivation histories, comparative whole‐genome analyses of established HEK293 variants as well as newly suspension‐adapted cells revealed a shared, common set of mutations linked to cell ...
Georg Smesnik +4 more
wiley +1 more source
Enhancing Agricultural Sustainability by Improving the Efficiency of Lignocellulosic Biomass Utilization in the Ruminant Diet via Solid-State Fermentation with White-Rot Fungi: A Review. [PDF]
MicroorganismsYan Q +10 more
europepmc +1 more source
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.ABSTRACT Balanites aegyptiaca (BA) is a plant of paramount potential for the management of diabetes mellitus. The study investigates in silico studies of natural library compounds including that from BA with the assistance of network pharmacology. Balanitesin (compound 1) exhibited the highest docking score and binding free energy (∆G) values of −14 ...
Surendra Kumar Gautam +8 more
wiley +1 more source
Transcriptome response of the white-rot fungus Trametes versicolor to hybrid poplar exhibiting unique lignin chemistry. [PDF]
Fungal Biol BiotechnolAlzabaidi AR +4 more
europepmc +1 more source
ChemBioEng Reviews, Volume 13, Issue 1, February 2026.Microorganisms generate versatile biosurfactants with a wide range of uses. Although cost issues still exist, industrial interest is growing because to the advantages of sustainability, which are enhanced by genetic engineering; life cycle evaluation is crucial for scalable, environmentally responsible production.
Lavanya M., Rishabh Agarwala
wiley +1 more source
Biocatalytic Synthesis of Diamondoid Diols by the Brown‐Rot Fungus Wolfiporia cocos
ChemBioChem, Volume 27, Issue 3, February 2026.Wolfiporia cocos cultures were tested for CH‐oxidative activity using rigid diamondoid substrates. Adamantane derivatives gave typical diols similar to known chemical oxidations, while diamantane‐4‐ol showed unusual selectivity, forming rare 4,9‐ and 1,9‐diols.
Valeriia V. Nikitenkova +3 more
wiley +1 more source
Intraspecies Variation Offers Potential to Improve White Rot Fungi for Increasing Degradability of Lignocellulose for Ruminants. [PDF]
J Fungi (Basel)Sonnenberg ASM +3 more
europepmc +1 more source
The Genetic and Morphological Basis of Local Adaptation to Elevational Extremes in an Alpine Finch
Ecology and Evolution, Volume 16, Issue 2, February 2026.We investigated morphological and genetic variation in the Sierra Nevada Gray‐crowned Rosy Finch to identify traits important for local adaptation in alpine environments. By combining trait measurements with genome‐wide analyses, we uncovered loci linked to thermoregulation, altitude adaptation, and cold tolerance.
Erica C. N. Robertson +6 more
wiley +1 more source