Results 71 to 80 of about 60,772 (341)

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A., Chen, Ichun Anderson, Cheng, Xiaojun, Erdener, Sefik Evren, Kılıç, Kıvılcım, Kura, Sreekanth, Lee, Blaire Ss, Postnov, Dmitry, Sunil, Smrithi, Tang, Jianbo   +9 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Evaluation of Remineralizing Efficacy of Calcium Sucrose Phosphate: A Systematic Review of Studies

Journal of Indian Orthodontic Society, 2019
Background: Despite improved oral hygiene regime and availability of preventive formulations, dental caries continues to be a global dental problem. Calcium sucrose phosphate (CaSP) is a remineralizing agent with cariostatic action, which is commonly ...
Ashok Karad, Prashant Dhole
doaj   +1 more source

The chromatograph evaluation of white spot lesion treated with magnesium gel and diode laser: an in vitro study [PDF]

Romanian Journal of Stomatology
Objective. White spot lesions are one of the most common concerns of orthodontic therapy. The present study was accomplished to evaluate the ability of Magnesium gel at different concentration and diode laser in combination compared with commercially ...
Rasha M. Salim, Sarmad S. Salih. Al Qassar, Aisha A. Qasim   +2 more
doaj   +1 more source

Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]

, 2011
Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico, Heinze, Hans-Jochen, Hopf, Jens-Max, Krebs, Ruth, Noesselt, Toemme, Schoenfeld, Mircea A, Stoppel, Christian M   +6 more
core   +2 more sources

White spot lesions: A literature review

Journal of Pediatric Dentistry, 2015
There has been a paradigm shift from Black's extension for prevention to a minimal intervention approach in the recent time. To diagnose earliest stages of enamel demineralization, accurate and reliable detection of white spot lesions is very important.
Sidhant Pathak, KorishettarBasavaraj Roopa, Parameswarappa Poornima, IndavaraEregowda Neena   +3 more
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Electron Mıcroscobıc Investıgatıon Of The Effects Of Dıfferent Cement-Son Whıte Spot Lesıons Occurıng Under The Orthodontıc Bands

Turkish Journal of Orthodontics, 1995
The purpose of our study is to examine the effects of different cements on enamel decalcification in order to prevent the White Spot lesions which came into life under the orthodontic bands.
Celal Oker, Deniz Sağdıç, Osman Bengi, Hüseyin Ölmez   +3 more
doaj   +1 more source

Cognitive Deficits Are Associated with Frontal and Temporal Lobe White Matter Lesions in Middle-Aged Adults Living in the Community [PDF]

, 2015
BACKGROUND The association between brain white matter lesions and cognitive impairment in old age is well established. However, little is known about this association in midlife.
Anstey, Kaarin, Bunce, David, Burns, Richard, Cherbuin, Nicolas, Christensen, Helen, Sachdev, Perminder S., Wen, Wei   +6 more
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source