Results 91 to 100 of about 133,425 (365)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Color of Kinship [PDF]

open access: yes, 2017
This Article addresses the need for family law scholarship that better theorizes and grapples with how race informs American life in the 21st Century. Family law scholars have been instrumental in documenting and advocating for recognition of the “new ...
Lenhardt, Robin A.
core   +1 more source

Decorating the Neolithic: an Evaluation of the Use of Plaster in the Enhancement of Daily Life in the Middle Pre-pottery Neolithic B of the Southern Levant [PDF]

open access: yes, 2012
During the Middle Pre-pottery Neolithic B in the southern Levant the use of lime plaster in both ritual and domestic contexts increased significantly relative to previous periods.
Clarke, Joanne
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Reinventing Significance: Reflections on Recent Whiteness Studies in Zimbabwe

open access: yesAfrica Spectrum, 2014
Review Article: Josephine Lucy Fisher (2010), Pioneers, Settlers, Aliens, Exiles: The Decolonisation of White Identity in Zimbabwe, Canberra: Australian National University Press, ISBN 978-1-921-66614-8 (pbk.), xiii + 276 pp. David McDermott Hughes (2010)
Rory Pilossof
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Reader Expectation and the Ethnic Rhetorics: The Problem of the Passing Subaltern in Who Would Have Thought It? [PDF]

open access: yes, 2005
Mrs. Norval... hoped...Lola might be now all black or all white, no matter which, only not with those ugly white spots. - Who Would Have Thought It? 1872 (78) But these snowy, equable and smooth spots ... sometimes occur amongst our own people.
Stevenson, Pascha A.
core   +1 more source

WHITE HEAT: racism, under-achievement and white working-class boys [PDF]

open access: yes, 2000
The article examines students' experience of inner-city education in one of England’s most disadvantaged areas. In particular, we reflect on the views of white working class boys, a group that has recently been identified by policy-makers and the media ...
Gillborn, David, Kirton, Alison
core   +2 more sources

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