Results 61 to 70 of about 8,517,970 (127)
Pediatric Dermatology, Volume 41, Issue 6, Page 1040-1046, November/December 2024.Abstract Janus kinase inhibitors (JAKi) are drugs that block tyrosine kinases responsible for transducing cytokine signals. The first JAKi was approved by the US Food and Drug Administration (FDA) in 2011 to treat rheumatoid arthritis in adults. A pediatric indication was not approved until 8 years later, for acute graft‐versus‐host disease. Since then,
Sahithi Talasila +4 more
wiley +1 more source
Annals of Neurology, Volume 96, Issue 4, Page 802-811, October 2024.Objective Multiple acyl‐coenzyme A dehydrogenase deficiency (MADD) is a disorder of fatty acid oxidation and considered an inborn error of metabolism. In recent years, we have diagnosed an increasing number of patients where, despite extensive investigation, no disease‐causing mutations have been found. We therefore investigated a cohort of consecutive
Sofie Sunebo +3 more
wiley +1 more source
Cardiovascular toxicity with CTLA‐4 inhibitors in cancer patients: A meta‐analysis
Cancer Innovation, Volume 3, Issue 3, June 2024.1. CTLA‐4 inhibitors restore the T cell immune response against tumor cells. Tumors and cardiomyocytes, shared some muscle‐specific antigens, which trigger a cross‐reactivity with T cells. The inhibitors make cardiac cells susceptible to injury. 2. CTLA‐4 inhibitors significantly increased the incidence of all‐grade cardiovascular toxicity and severe ...
Huiyi Liu +6 more
wiley +1 more source
Annual distribution of AE reports for TXA in VigiAccess.
Annual distribution of AE reports for TXA in VigiAccess.
Jing Feng (177843) +2 more
core +1 more source
Pharmacoepidemiology and Drug Safety, Volume 33, Issue 5, May 2024.Abstract Purpose Pulmonary fibrosis (PF) is a severe, progressive disease, which may be caused by exposure to certain medications. Methods We queried the U.S. FDA Adverse Event Reporting System (FAERS) from 2000 to 2022, using the search terms “pulmonary fibrosis” and “idiopathic pulmonary fibrosis” and excluded reports with patients under the age of ...
Kenneth L. McCall +6 more
wiley +1 more source
International Journal of Bipolar Disorders, 2018 Background Cancer had never been considered as a relevant problem in patients treated with lithium until 2015, when a document published by the European Medicine Agency concluded that long-term use of lithium might induce renal tumors. A few months later,
Luca Ambrosiani +5 more
doaj +1 more source
Scientific ReportsViloxazine and dextroamphetamine as newly approved drugs for the medical treatment of Attention Deficit Hyperactivity Disorder (ADHD) in recent years give new options for the treating of related disorders, including anxiety, and depression.
Lijun Wang, Qingyang Kong, Yixuan Li
doaj +1 more source
Background/Objectives: Antineoplastic therapies have improved cancer survival but remain a major source of treatment-related cardiotoxicity. Comparative global pharmacovigilance evidence across anthracyclines, anti-HER2, and anti-VEGF therapies remains limited. Methods: A retrospective disproportionality study was conducted using Individual Case Safety
Esteban Zavaleta-Monestel +5 more
openaire +1 more source
Identification of PT signals for TXA using disproportionality analysis in VigiAccess.
Identification of PT signals for TXA using disproportionality analysis in VigiAccess.
Jing Feng (177843) +2 more
core +1 more source
The top 50 Signal strength of AEs at the PT level ranked by ROR for TXA in VigiAccess.
The top 50 Signal strength of AEs at the PT level ranked by ROR for TXA in VigiAccess.
Jing Feng (177843) +2 more
core +1 more source