Results 71 to 80 of about 8,517,970 (127)

Real-world adverse event profiles of Zuranolone and Brexanolone based on FAERS and VigiAccess databases: An observational study

open access: yes
Zuranolone and Brexanolone are Food and Drug Administration-approved novel agents for postpartum depression, yet real-world post-marketing safety data for the two drugs remain insufficient.
Liqun Chi   +3 more
core   +1 more source

Analysis of adverse reaction characteristics of four biologics for the treatment of chronic sinusitis with nasal polyps: A descriptive analysis from WHO-VigiAccess

open access: yesAmerican Journal of Otolaryngology
Chronic rhinosinusitis with nasal polyps (CRSwNP) imposes a significant global disease burden. However, systematic comparisons of adverse drug reaction (ADR) profiles among these agents remain scarce, necessitating large-scale pharmacovigilance evaluation.Utilizing the WHO VigiAccess database, we analyzed 402,778 ADR reports for four biologics ...
Xiaobi, Fang, Tingfeng, Zhou, Fan, Ye
openaire   +2 more sources

Real-world safety signals of fezolinetant in women with menopausal vasomotor symptoms: a pharmacovigilance analysis of the WHO VigiAccess database

open access: yes
Objectives: To characterize the real-world safety profile of fezolinetant, a neurokinin-3 receptor antagonist approved for the treatment of menopausal vasomotor symptoms, using adverse event reports from the WHO ...
Xiaoling Gao   +7 more
core   +1 more source

A Real-World Data Analysis of Adverse Drug Reactions Associated with Neuroprotective Agents: Insights from WHO-VigiAccess

open access: yes
Abstract Introduction: Sensorineural hearing loss (SNHL) is a common sensory disorder characterized by auditory nerve damage and cochlear dysfunction, often driven by oxidative stress, excitotoxicity, and neuroinflammation. Neuroprotective agents such as Cerebrolysin, Citicoline, Flunarizine, and Mecobalamin have demonstrated efficacy in ...
Shuainan Chen   +4 more
openaire   +1 more source

Psychiatric Adverse Events Associated with GLP-1 Receptor Agonists: Evidence of Intraclass Heterogeneity in the WHO VigiBase Global Database

open access: yesEndocrines
Background/Objectives: Concerns regarding the psychiatric safety profile of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have increased since the 2023 European Medicines Agency (EMA) and U.S. Food and Drug Administration (FDA) reviews.
Esteban Zavaleta-Monestel   +5 more
doaj   +1 more source

VigiAccess Covid-19 dataset

open access: yes
Background: The monitoring and analysis of adverse drug reactions (ADR’s) play a pivotal role in ensuring drug safety. In the context of a public health emergency of international concern (PHEIC), and the roll out of experimental COVID-19 vaccines, the ...
Theresa Lawrie, Andrew Bryant
core   +1 more source

WHO Monographs on Medicinal Plants Commonly Used in the Newly Independent States (NIS)

open access: yes, 2010
Since 1999, WHO has published four volumes of WHO monographs on selected medicinal plants, totaling 116 monographs. Despite the increasing use of herbal medicines, there is still a significant lack of research data in this field, so the WHO monographs ...
World Health Organization (WHO)
core   +1 more source

Spectrum and signals of medication-associated cognitive disorder: a comprehensive disproportionality analysis with cross-database validation

open access: yesFrontiers in Pharmacology
ObjectiveThe clinical risk of cognitive disorders linked to various drugs is not well-defined. This study aimed to identify medications with notable signals for drug-related cognitive disorders and evaluate whether their US Food and Drug Administration ...
Hao Wen, Yajie Dong, Ruiting Wang
doaj   +1 more source

WHO launches CoViNet: a global network for coronaviruses [PDF]

open access: yes
WHO has launched a new network for coronaviruses, CoViNet, to facilitate and coordinate global expertise and capacities for early and accurate detection, monitoring and assessment of SARS-CoV-2, MERS-CoV and novel coronaviruses of public health ...
WHO Media Team
core  

The real-world analysis of tinnitus-related adverse events across systemic medications: a pharmacovigilance study based on the FAERS and WHO-VigiAccess databases

open access: yes
Background Tinnitus is a prevalent and often persistent symptom that imposes a substantial psychological and functional burden. Beyond disease-related mechanisms, accumulating real-world observations suggest that tinnitus may also ...
Zhuohao Li   +4 more
core   +1 more source

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