Results 81 to 90 of about 309 (92)

Adverse events following the use of immune checkpoint inhibitors: An analysis of the WHO VigiAccess database.

Journal of Clinical Oncology, 2019
e13118 Background: Immune checkpoint inhibitors (ICIs), especially ipilimumab (ipi) and nivolumab (nivo), have received approvals from the U.S. Food and Drug Administration for the treatment of multiple tumor types. These medications have shown great promise in the treatment of several malignancies but are associated with immune-related adverse ...
Nikita Nikita   +5 more
openaire   +1 more source

Safety study on adverse events of zanubrutinib based on WHO-VigiAccess and FAERS databases

Expert Opinion on Drug Safety
The study endeavors to elucidate AE signals associated with zanubrutinib data from the WHO-VigiAccess and FAERS databases. The aim is to furnish robust scientific evidence to inform clinical practice and regulatory decisions.We meticulously extracted all AE breports tied to zanubrutinib from the both databases, encompassing the period from the drug's ...
Qiaofang, Liang   +6 more
exaly   +3 more sources

Descriptive Analysis of Adverse Drug Events of Three mTOR Inhibitors Using WHO-VigiAccess

Current Drug Safety
Introduction: The mechanistic target of rapamycin (mTOR) pathway regulates cell growth, metabolism, and survival. Its dysregulation contributes to cancer, autoimmune disorders, neurodegeneration, and aging. While mTOR inhibitors such as Sirolimus, Everolimus, and Temsirolimus are therapeutically valuable, they ...
Prerna Bhati   +2 more
openaire   +1 more source

Characterization of Adverse Drug Effects to Three Radiopharmaceuticals: A Descriptive Analysis from WHO-VigiAccess

Cancer Biotherapy and Radiopharmaceuticals
Background: Radiopharmaceuticals are being used more frequently to treat neuroendocrine tumors and advanced prostate cancer; however, their clinical application is associated with adverse drug reactions (ADRs) that may affect patient safety.
Yiheng Jin   +5 more
openaire   +1 more source

Class-level differences and within-class heterogeneity in heart failure reporting with immune checkpoint inhibitors: a WHO vigiaccess pharmacovigilance study

European Journal of Heart Failure
Abstract Background/Introduction Immune checkpoint inhibitors (ICIs) have revolutionised cancer care, but immune-related cardiotoxicity remains poorly catalogued beyond fulminant myocarditis. Emerging case series describe a clinically silent, acute left ventricular decompensation phenotype that
Y Shhab   +6 more
openaire   +1 more source

Adverse events following immunization associated with coronavirus disease 2019 (COVID-19) vaccines: A descriptive analysis from VigiAccess

Human Vaccines and Immunotherapeutics, 2022
Joseph Attakorah   +2 more
exaly  

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