Results 51 to 60 of about 912,763 (246)

PennCNV in whole-genome sequencing data

BMC Bioinformatics, 2017
Background The use of high-throughput sequencing data has improved the results of genomic analysis due to the resolution of mapping algorithms. Although several tools for copy-number variation calling in whole genome sequencing have been published, the ...
Leandro de Araújo Lima, Kai Wang
doaj   +1 more source

Whole-genome sequencing analysis of semi-supercentenarians

eLife, 2021
Extreme longevity is the paradigm of healthy aging as individuals who reached the extreme decades of human life avoided or largely postponed all major age-related diseases.
Paolo Garagnani, Julien Marquis, Massimo Delledonne, Chiara Pirazzini, Elena Marasco, Katarzyna Malgorzata Kwiatkowska, Vincenzo Iannuzzi, Maria Giulia Bacalini, Armand Valsesia, Jerome Carayol, Frederic Raymond, Alberto Ferrarini, Luciano Xumerle, Sebastiano Collino, Daniela Mari, Beatrice Arosio, Martina Casati, Evelyn Ferri, Daniela Monti, Benedetta Nacmias, Sandro Sorbi, Donata Luiselli, Davide Pettener, Gastone Castellani, Claudia Sala, Giuseppe Passarino, Francesco De Rango, Patrizia D'Aquila, Luca Bertamini, Nicola Martinelli, Domenico Girelli, Oliviero Olivieri, Cristina Giuliani, Patrick Descombes, Claudio Franceschi   +34 more
doaj   +1 more source

Whole-genome sequencing data of Kazakh individuals

BMC Research Notes, 2021
Objectives Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today is the multi-ethnic country with ...
Ulykbek Kairov, Askhat Molkenov, Saule Rakhimova, Ulan Kozhamkulov, Aigul Sharip, Daniyar Karabayev, Asset Daniyarov, Joseph H.Lee, Joseph D.Terwilliger, Ainur Akilzhanova, Zhaxybay Zhumadilov   +10 more
doaj   +1 more source

novoBreak: local assembly for breakpoint detection in cancer genomes. [PDF]

, 2017
We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Boutros, Paul, Chen, Junjie, Chen, Ken, Chen, Tenghui, Chong, Zechen, Ding, Li, Fan, Xian, Gao, Min, Lee, Anna Y, Ruan, Jue, Zhou, Wanding   +10 more
core  

Whole-Genome Sequencing of Two Bartonella bacilliformis Strains [PDF]

, 2016
Bartonella bacilliformis is the causative agent of Carrion's disease, a highly endemic human bartonellosis in Peru. We performed a whole-genome assembly of two B.
Casadellà, Maria, Espinoza-Culupú, Abraham, García de la Guarda, Ruth, Guillén, Yolanda, Noguera Julian, Marc, Paredes, Roger, Ruiz, Joaquim   +6 more
core   +2 more sources

Multi-country and intersectoral assessment of cluster congruence between pipelines for genomics surveillance of foodborne pathogens

Nature Communications
Different laboratories employ different Whole-Genome Sequencing (WGS) pipelines for Food and Waterborne disease (FWD) surveillance, casting doubt on the comparability of their results and hindering optimal communication at intersectoral and international
Verónica Mixão, Miguel Pinto, Holger Brendebach, Daniel Sobral, João Dourado Santos, Nicolas Radomski, Anne Sophie Majgaard Uldall, Arkadiusz Bomba, Michael Pietsch, Andrea Bucciacchio, Andrea de Ruvo, Pierluigi Castelli, Ewelina Iwan, Sandra Simon, Claudia E. Coipan, Jörg Linde, Liljana Petrovska, Rolf Sommer Kaas, Katrine Grimstrup Joensen, Sofie Holtsmark Nielsen, Kristoffer Kiil, Karin Lagesen, Adriano Di Pasquale, João Paulo Gomes, Carlus Deneke, Simon H. Tausch, Vítor Borges   +26 more
doaj   +1 more source

Typing methods based on whole genome sequencing data

One Health Outlook, 2020
Whole genome sequencing (WGS) of foodborne pathogens has become an effective method for investigating the information contained in the genome sequence of bacterial pathogens.
Laura Uelze, Josephine Grützke, Maria Borowiak, Jens Andre Hammerl, Katharina Juraschek, Carlus Deneke, Simon H. Tausch, Burkhard Malorny   +7 more
doaj   +1 more source

Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research

BMC Medical Genomics, 2012
Background Massively-parallel sequencing (MPS) technologies create challenges for informed consent of research participants given the enormous scale of the data and the wide range of potential results.
Facio Flavia M, Sapp Julie C, Linn Amy, Biesecker Leslie G   +3 more
doaj   +1 more source

Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications

Revista Panamericana de Salud Pública, 2023
Whole-genome sequencing is becoming the gold standard for pathogen characterization and offers considerable advantages for understanding the evolution and dissemination of new determinants of antimicrobial resistance. Despite the benefits of whole-genome
William Calero-Cáceres, Nimer Ortuño-Gutiérrez, Temmy Sunyoto, Cícero-Armídio Gomes-Dias, Carlos Bastidas-Caldes, Ma. Soledad Ramírez, Anthony D. Harries   +6 more
doaj   +1 more source

Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo. [PDF]

, 2014
Staphylococcus aureus is a commensal and major pathogen of humans and animals. Comparative genomics of S. aureus populations suggests that colonization of different host species is associated with carriage of mobile genetic elements (MGE), particularly ...
Gould, KA, Lindsay, JA, Lloyd, DH, Loeffler, A, McCarthy, AJ, Witney, AA   +5 more
core   +2 more sources