Results 61 to 70 of about 552,282 (159)

Whole genome sequencing in paediatric channelopathy and cardiomyopathy

Frontiers in Cardiovascular Medicine
BackgroundPrecision medicine in paediatric cardiac channelopathy and cardiomyopathy has a rapid advancement over the past years. Compared to conventional gene panel and exome-based testing, whole genome sequencing (WGS) offers additional coverage at the ...
Sit Yee Kwok, Anna Ka Yee Kwong, Julia Zhuo Shi, Connie Fong Ying Shih, Mianne Lee, Christopher C. Y. Mak, Martin Chui, Sabrina Tsao, Brian Hon Yin Chung   +8 more
doaj   +1 more source

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

Infection and Drug Resistance, 2018
Mallika Lavania,1 Itu Singh,1 Ravindra P Turankar,1 Anuj Kumar Gupta,2 Madhvi Ahuja,1 Vinay Pathak,1 Utpal Sengupta1 1Stanley Browne Laboratory, The Leprosy Mission Trust India, TLM Community Hospital Nand Nagari, 2Agilent Technologies India Pvt Ltd ...
Lavania M, Singh I, Turankar RP, Gupta AK, Ahuja M, Pathak V, Sengupta U   +6 more
doaj  

Editorial: Whole Genome Sequencing for rare diseases

Frontiers in Medicine, 2023
Chiara Di Resta, Chiara Di Resta, Valeria D'Argenio, Valeria D'Argenio   +3 more
doaj   +1 more source

Whole-Genome Sequencing and Epidemiological Investigation of Tuberculosis Outbreaks in High Schools in Hunan, China

Infection and Drug Resistance, 2022
Zuhui Xu,1,2,* Haican Liu,3,* Yanping Liu,4,* Yi Tang,2 Yunhong Tan,2 Peilei Hu,2 Chuanfang Zhang,2 Chongguang Yang,4 Kanglin Wan,3 Qiaozhi Wang2 1Xiangya School of Public Health, Central South University, Changsha, 410078, People’s Republic ...
Xu Z, Liu H, Liu Y, Tang Y, Tan Y, Hu P, Zhang C, Yang C, Wan K, Wang Q   +9 more
doaj  

Improved influenza A whole-genome sequencing protocol

Frontiers in Cellular and Infection Microbiology
Influenza A virus poses significant public health challenges due to its high mutation rate and zoonotic potential. Whole-genome sequencing (WGS) is crucial for monitoring and characterizing these viruses.
Iryna V. Goraichuk, Jacquline Risalvato, Mary Pantin-Jackwood, David L. Suarez   +3 more
doaj   +1 more source

Lessons and pitfalls of whole genome sequencing

Practical Neurology
Whole-genome sequencing (WGS) has recently become the first-line genetic investigation for many suspected genetic neurological disorders. While its diagnostic capabilities are innumerable, as with any test, it has its limitations. Clinicians should be aware of where WGS is extremely reliable (detecting single-nucleotide variants), where its reliability
Christopher J Record, Mary M Reilly
openaire   +3 more sources

Whole genome sequencing for lung cancer.

Journal of thoracic disease, 2012
Lung cancer is a leading cause of cancer related morbidity and mortality globally, and carries a dismal prognosis. Improved understanding of the biology of cancer is required to improve patient outcomes. Next-generation sequencing (NGS) is a powerful tool for whole genome characterisation, enabling comprehensive examination of somatic mutations that ...
Daniels, Marissa, Goh, Felicia, Wright, Casey M., Sriram, Krishna B., Relan, Vandana, Clarke, Belinda E., Duhig, Edwina E., Bowman, Rayleen V., Yang, Ian A., Fong, Kwun M.   +9 more
openaire   +3 more sources

Marching toward 100% whole genome sequencing

Frontiers in Genetics, 2016
Yih-Horng eShiao
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IMPLEMENTATION OF WHOLE GENOME SEQUENCING FOR BACTERIA GENOTYPING [PDF]

Postępy Mikrobiologii, 2018
Daria Artyszuk, Tomasz Wołkowicz
doaj   +1 more source

Whole Genome Sequencing [PDF]

, 2019
openaire   +3 more sources