Results 41 to 50 of about 3,960,512 (303)

Genomic data of an environmental Escherichia coli isolate shows high resemblance to E. coli K-12 reference strain MG1655

Data in Brief, 2021
Escherichia coli species exhibits a high genomic diversification from evolution, mobile genetic elements and recombination. An environmental E. coli isolate, ‘JHI_5025’ from a crop trial appeared to be clonally related to the historical reference isolate
Nicola Holden
doaj   +1 more source

Optical mapping as a routine tool for bacterial genome sequence finishing [PDF]

, 2007
Background: In sequencing the genomes of two Xenorhabdus species, we encountered a large number of sequence repeats and assembly anomalies that stalled finishing efforts.
Norton, S., Miller, N., Zijin Du, Goldman, Barry S., Latreille Phil, Bode, Helge Björn, Henkhaus John, Forst, Steve, John Henkhaus, Goodrich-Blair, H., Miller, Nancy, Slater Steven, Stacie Norton, Bode, H., Goldman Barry S, Henkhaus, J., Gaudriault, S., Steve Forst, Creg Darby, Gaudriault Sophie, Darby Creg, Goldman, B., Gaudriault, Sophie, Darby, C., Du, Z., Goodner, B., Norton, Stacie, Sophie Gaudriault, Miller Nancy, Goodrich-Blair, Heidi, Henkhaus, John, Heidi Goodrich-Blair, Gaudriault, Sophie, S., Latreille, Phil, Slater, S., Goodrich-Blair Heidi, Goodner, Brad, Goodner Brad, Latreille, P., Bode, Helge B., Nancy Miller, Norton Stacie, Brad Barbazuk, Phil Latreille, Steven Slater, Slater, Steven, Forst Steve, Helge B Bode, Forst, S., Barbazuk, Brad, Barbazuk Brad, Du, Zijin, Bode Helge B, Barry S Goldman, Du Zijin, Brad Goodner, Barbazuk, B., Darby, Creg   +57 more
core   +1 more source

Whole-genome sequencing depth and coverage.

, 2023
A) Histogram of 1,035 whole-genome sequencing (WGS) samples from APIC and URECA by mean depth of coverage. B) Histogram of WGS samples based on proportion of genome covered at 20x, 25x, and 30x depth.
Deepa Rastogi (6635723), Dan Nicolae (32963), Selene Clay (14425315), Meyer Kattan (9443480), James E. Gern (7512719), Agustin Calatroni (14425318), Michael G. Sherenian (14425321), Andrew H. Liu (13886609), William Wentworth-Sheilds (697345), Matthew Dapas (9016484), Matthew C. Altman (4804422), William W. Busse (8189409), Patrice M. Becker (14425324), Robert A. Wood (3279096), Haejin Kim (833850), Gurjit K. Khurana Hershey (7889699), Carole Ober (259474), Emma E. Thompson (11544512), Cynthia M. Visness (5422457), Melanie Makhija (13886600), Joanne E. Sordillo (8451417), Rebecca S. Gruchalla (13886603), Leonard B. Bacharier (9443486), Diane R. Gold (11732568), Michelle A. Gill (13886606), George T. O’Connor (7782248), Daniel J. Jackson (7513151)   +26 more
core   +1 more source

Algorithms for whole genome shotgun sequencing [PDF]

Proceedings of the third annual international conference on Computational molecular biology, 1999
A monumental achievement in the history of science, the sequencing of the entire human genome, will soon be reached. The Human Genome Project (HGP) has been working toward this goal since 1990 using a two-tiered strategy. Recently it was proposed that using a whole-genome shotgun approach to sequence the genome would be faster and less costly.
Eric L. Anson, Eugene W. Myers
openaire   +2 more sources

Whole genome sequencing in families with oligodontia

Oral Diseases, 2023
Abstract Background/Objectives Tooth agenesis (TA) is among the most common malformations in humans. Although several causative mutations have been described, the genetic cause often remains elusive. Here, we test whether whole genome sequencing (WGS) could bridge this diagnostic gap.
Janna Mitscherling, Henrike L. Sczakiel, Olga Kiskemper‐Nestorjuk, Sibylle Winterhalter, Stefan Mundlos, Theodosia Bartzela, Martin A. Mensah   +6 more
openaire   +3 more sources

Routine use of microbial whole genome sequencing in diagnostic and public health microbiology [PDF]

, 2012
This work is partly supported by funding from the Medical Research Council, the European Developing Country Clinical Trials Partnership, the Global Alliance for TB Drug Development, and the European Union.Whole genome sequencing (WGS) promises to be ...
Holden, MTG, Matthew T G Holden, Mark Farrington (148224), Cartwright, EJP, Matthew T. G. Holden (130258), Brown, Nicholas M., Sharon J Peacock, Bentley, SD, Ellington, Matthew J., Claudio U Köser, Parkhill, J, Stephen D. Bentley (137281), Stephen H Gillespie, Stephen D Bentley, Köser, CU, Bentley, Stephen D., Julian Parkhill (30393), Holden, Matthew T. G., Julian Parkhill, Peacock, Sharon J., Edward J. P. Cartwright (148213), Koeser, Claudio U., Peacock, SJ, Stephen H. Gillespie (148218), Edward J P Cartwright, Gordon Dougan, Matthew J. Ellington (148208), Farrington, M, Cartwright, Edward J. P., Dougan, Gordon, Nicholas M Brown, Parkhill, Julian, Mark Farrington, Gordon Dougan (30395), Farrington, Mark, Claudio U. Köser (148202), Gillespie, Stephen H., Matthew J Ellington, Brown, NM, Sharon J. Peacock (35782), Gillespie, SH, Ellington, MJ, Nicholas M. Brown (148222), Dougan, G, Gillespie, Stephen H.; id_orcid   +44 more
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Whole genome sequencing of breast cancer [PDF]

APMIS, 2019
Breast cancer was the first to take advantage of targeted therapy using endocrine therapy, and for up to 20% of all breast cancer patients a further significant improvement has been obtained by HER2‐targeted therapy. Greater insight in precision medicine is to some extent driven by technical and computational progress, with the first wave of a true ...
Rossing, Maria, Sørensen, Claus Storgaard, Ejlertsen, Bent, Nielsen, Finn Cilius   +3 more
openaire   +4 more sources

Complete mitochondrial genomes of Culicoides brevitarsis and Culicoides imicola biting midge vectors of Bluetongue Virus

Mitochondrial DNA. Part B. Resources
Biting midges (Culicoides spp.) are important vectors of several insect borne arboviruses but are underrepresented in terms of availability of high-resolution genomic resources. We assembled and annotated complete mitochondrial genomes for two Culicoides
Khandaker Asif Ahmed, Anjana Karawita, Melissa J. Klein, Luana Fiorella Mincarelli, Barbara Secondini, Giuseppe Satta, Massimo Ancora, Cipriano Foxi, Marco Di Domenico, Michela Quaglia, Maria Goffredo, Alessio Lorusso, Cesare Cammà, Leon Court, Rahul V. Rane, Tom K. Walsh, Prasad N. Paradkar, Debbie Eagles, Gunjan Pandey, Christopher M. Hardy   +19 more
doaj   +1 more source

Human Whole-Genome Shotgun Sequencing [PDF]

Genome Research, 1997
Large-scale sequencing of the human genome is now under way (Boguski et al. 1996; Marshall and Pennisi 1996). Although at the beginning of the Genome Project, many doubted the scientific value of sequencing the entire human genome, these doubts have evaporated almost entirely (Gibbs 1995; Olson 1995).
J L, Weber, E W, Myers
openaire   +2 more sources

Genomic Characterization of a Wild-Type Bovine alphaherpesvirus 1 (BoAHV-1) Strain Isolated in an Outbreak in Central Italy

Viruses
Bovine alphaherpesvirus-1 (BoAHV-1) infection is common in cattle worldwide. However, information on the spread of BoAHV-1-circulating strains in Italy remains limited.
Stefano Petrini, Valentina Curini, Cecilia Righi, Cesare Cammà, Valeria Di Lollo, Elena Tinelli, Luana Fiorella Mincarelli, Elisabetta Rossi, Giulia Costantino, Barbara Secondini, Silvia Pirani, Monica Giammarioli, Francesco Feliziani   +12 more
doaj   +1 more source