Results 21 to 30 of about 905,445 (296)

Human whole genome sequencing in South Africa

Scientific Reports, 2021
The advent and evolution of next generation sequencing has considerably impacted genomic research. Until recently, South African researchers were unable to access affordable platforms capable of human whole genome sequencing locally and DNA samples had ...
Brigitte Glanzmann, Tracey Jooste, Samira Ghoor, Richard Gordon, Rizwana Mia, Jun Mao, Hao Li, Patrick Charls, Craig Douman, Maritha J. Kotze, Armand V. Peeters, Glaudina Loots, Monika Esser, Caroline T. Tiemessen, Robert J. Wilkinson, Johan Louw, Glenda Gray, Robin M. Warren, Marlo Möller, Craig Kinnear   +19 more
doaj   +1 more source

Human Whole-Genome Shotgun Sequencing [PDF]

Genome Research, 1997
Large-scale sequencing of the human genome is now under way (Boguski et al. 1996; Marshall and Pennisi 1996). Although at the beginning of the Genome Project, many doubted the scientific value of sequencing the entire human genome, these doubts have evaporated almost entirely (Gibbs 1995; Olson 1995).
J L, Weber, E W, Myers
openaire   +2 more sources

Occurrence and temporal distribution of extended-spectrum β-lactamase-producing Escherichia coli in clams from the Central Adriatic, Italy

Frontiers in Microbiology, 2023
The spread of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is a major public health issue. Bivalves are filter-feeder animals capable of bioaccumulating the microorganisms present in water.
Francesca Leoni, Luca Sacchini, Silvia Pieralisi, Gabriele Angelico, Chiara Francesca Magistrali, Lucilla Cucco, Francesca Romana Massacci, Elisa Albini, Anna Duranti, Cesare Cammà, Barbara Secondini, Antonio Rinaldi, Francesca Barchiesi   +12 more
doaj   +1 more source

A Distributed Whole Genome Sequencing Benchmark Study

Frontiers in Genetics, 2020
Population sequencing often requires collaboration across a distributed network of sequencing centers for the timely processing of thousands of samples.
Richard D. Corbett, Robert Eveleigh, Joe Whitney, Namrata Barai, Mathieu Bourgey, Eric Chuah, Joanne Johnson, Richard A. Moore, Neda Moradin, Karen L. Mungall, Sergio Pereira, Miriam S. Reuter, Bhooma Thiruvahindrapuram, Richard F. Wintle, Jiannis Ragoussis, Lisa J. Strug, Jo-Anne Herbrick, Naveed Aziz, Steven J. M. Jones, Mark Lathrop, Stephen W. Scherer, Alfredo Staffa, Andrew J. Mungall   +22 more
doaj   +1 more source

Genomic data of an environmental Escherichia coli isolate shows high resemblance to E. coli K-12 reference strain MG1655

Data in Brief, 2021
Escherichia coli species exhibits a high genomic diversification from evolution, mobile genetic elements and recombination. An environmental E. coli isolate, ‘JHI_5025’ from a crop trial appeared to be clonally related to the historical reference isolate
Nicola Holden
doaj   +1 more source

Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit [PDF]

, 2015
Background: Cronobacter sakazakii is a member of the genus Cronobacter that has frequently been isolated from powdered infant formula (PIF) and linked with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
Dickins, B, Farbos, A, Forsythe, S, Masood, N, McNally, A, Moore, K, Paszkiewicz, K   +6 more
core   +2 more sources

Whole-genome sequencing and the clinician: a tale of two cities [PDF]

, 2014
Clinicians are faced with unprecedented opportunities to identify the genetic aetiologies of hitherto molecularly uncharacterised conditions via the use of high-throughput sequencing.
A. R. Foley, Dickens, Dubowitz, F. Muntoni, Foley, Gualandi, J. He, J. Kim, Jöbsis, Jöbsis, Kim, Lupski, M. G. Hanna, Mercuri, Mercuri, Morrow, N. M. Pearson, Pace, Pan, Phimister, R. D. S. Pitceathly, Straub   +21 more
core   +2 more sources

Whole-genome sequencing of Klebsiella pneumoniae isolates to track strain progression in a single patient with recurrent urinary tract infection [PDF]

, 2019
Klebsiella pneumoniae is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in women with frequent urinary tract infections (UTIs) may emanate from a ...
Minx, Patrick J, Rosen, David A, Wylie, Kristine M, Wylie, Todd N   +3 more
core   +5 more sources

Whole genome sequencing analysis of Plasmodium vivax using whole genome capture

BMC Genomics, 2012
Background Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen.
Bright A, Tewhey Ryan, Abeles Shira, Chuquiyauri Raul, Llanos-Cuentas Alejandro, Ferreira Marcelo U, Schork Nicholas J, Vinetz Joseph M, Winzeler Elizabeth A   +8 more
doaj   +1 more source

Rapid whole genome sequencing methods for RNA viruses

Frontiers in Microbiology, 2023
RNA viruses are the etiological agents of many infectious diseases. Since RNA viruses are error-prone during genome replication, rapid, accurate and economical whole RNA viral genome sequence determination is highly demanded.
Masayasu Misu, Masayasu Misu, Tomoki Yoshikawa, Satoko Sugimoto, Yuki Takamatsu, Takeshi Kurosu, Yukiteru Ouji, Masahide Yoshikawa, Masayuki Shimojima, Hideki Ebihara, Masayuki Saijo   +10 more
doaj   +1 more source