Results 21 to 30 of about 3,960,512 (303)

Whole Genome Sequencing in Cancer Clinics

EBioMedicine, 2015
Patients with a family history of cancer are being evaluated with single-gene or gene panel tests (LaDuca et al., 2014). The decreasing cost and potential to provide comprehensive genetic risk assessment makes whole genome sequencing (WGS) an attractive tool for understanding the genetic risk for cancer (Collins and Hamburg, 2013).
Ken Chen, Funda Meric-Bernstam
doaj   +3 more sources

Whole-Genome Sequencing in Cancer [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Genome sequencing of cancer has fundamentally advanced our understanding of the underlying biology of this disease, and more recently has provided approaches to characterize and monitor tumors in the clinic, guiding and evaluating treatment. Although cancer research is relying more on whole-genome characterization, the clinical application of genomics ...
Eric Y, Zhao, Martin, Jones, Steven J M, Jones   +2 more
openaire   +2 more sources

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
doaj   +1 more source

Pig genome sequence - analysis and publication strategy [PDF]

, 2010
Background The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome ...
Fredholm, M., Harlizius Barbara, Martien A M Groenen, Bolund, Lars, Rothschild Max F, Lee Kyung-Tai, Jane Rogers, Barbara Harlizius, Denis Milan, Groenen, M.A.M., Lee, Kyung-Tai, ?, ?, Uenishi, Hirohide, Jun Wang, Uenishi Hirohide, Churcher, C., Harlizius, Barbara, Lars Bolund, Lawrence B Schook, Alan L Archibald, Archibald Alan L, Fredholm, Merete, Groenen, Martien A. M., Schook, Lawrence B., Harlizius, B., Fredholm Merete, Archibald, A.L., The Swine Genome Sequencing Consortium,, Milan Denis, Bolund Lars, Groenen, Martien A.M., Rogers Jane, Wang Jun, Swine Genome Sequencing Consortium, Hirohide Uenishi, Groenen Martien AM, Rothschild, Max F., Bolund, L., Milan, Denis, Archibald, Alan L., Wang, Jun, Merete Fredholm, Kyung-Tai Lee, The Swine Genome Sequencing Consortium, -, Carol Churcher, Rogers, Jane, Churcher, Carol, Max F Rothschild, Schook Lawrence B, Churcher Carol   +49 more
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Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy [PDF]

, 2014
Whole-genome sequencing of the four isolates used in this study was supported by Wellcome Trust grant 098051, awarded to the Wellcome Trust Sanger Institute.
Theobald, V, Vandamme, P, Jacobs, J A, Vandamme, Peter, Currie, Bart J, Holden, Matthew T G, Jacobs, Jan, Jacobs, JA, Price, Erin P, Spratt, BG, Peacock, S J, Jacobs, Jan A, Parkhill, J, Holden, Matthew TG, Sarovich, DS, Sarovich, Derek S, Spratt, Brian G, Theobald, Vanessa, De Smet, B, Kham, Chun, Thong, P, Spratt, B G, Heng, Seiha, Holden, MT, Heng, S, Price, EP, Peacock, SJ, Currie, B J, Phe, Thong, Mayo, Mark, Holden, M T G, Parkhill, Julian, Mayo, M, Thong, Phe, Kham, C, De Smet, Birgit, Currie, BJ, Peacock, Sharon J, Sarovich, D S, Holden, Matthew T G; id_orcid   +39 more
core   +1 more source

Advances on whole genome sequencing in Triticeae

浙江大学学报. 农业与生命科学版, 2023
The Triticeae provides the important cereal crops, such as wheat, barley, and rye, which produces approximately 9×108 t annually, accounting for about 30% of the total global cereal production. However, Triticeae genomes are relatively difficult to be de
KUANG Liuhui, LI Qi, ZHANG Guoping
doaj   +1 more source

A pipeline for sample tagging of whole genome bisulfite sequencing data using genotypes of whole genome sequencing

BMC Genomics, 2023
Background In large-scale high-throughput sequencing projects and biobank construction, sample tagging is essential to prevent sample mix-ups. Despite the availability of fingerprint panels for DNA data, little research has been conducted on sample ...
Zhe Xu, Si Cheng, Xin Qiu, Xiaoqi Wang, Qiuwen Hu, Yanfeng Shi, Yang Liu, Jinxi Lin, Jichao Tian, Yongfei Peng, Yong Jiang, Yadong Yang, Jianwei Ye, Yilong Wang, Xia Meng, Zixiao Li, Hao Li, Yongjun Wang   +17 more
doaj   +1 more source

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting. [PDF]

, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny and transmission in well-resourced healthcare settings, yet the greatest burden of nosocomial ...
Thaipadungpanit, J, Holden, MTG, Cauchemez, S, Jombart, Thibaut, Nickerson, Emma K, Hongsuwan, M, Cori, A, Cauchemez, Simon, Holden, Matthew T G, Parkhill, J, Tong, SYC, Nickerson, EK, Day, Nicholas P, Day, NP, Fraser, C, Tong, Steven Y C, Fraser, Christophe, Limmathurotsakul, Direk, Limmathurotsakul, D, Wuthiekanun, Vanaporn, Peacock, SJ, Köser, Claudio U, Wuthiekanun, V, Cooper, BS, Cori, Anne, Parkhill, Julian, Cooper, Ben S, Thaipadungpanit, Janjira, Peacock, Sharon J, Jombart, T, Hongsuwan, Maliwan, Holden, Matthew T G; id_orcid, Koser, CU   +32 more
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Whole-genome sequencing identified somatic mutations in 100 gastric cancers

, 2022
This dataset contains list of somatic mutations identified by whole-genome sequencing in 100 gastric cancers. Whole genome sequencing data was generated from gastric tumor frozen tissues and blood leukocyte DNA.
Suet Yi Leung (9049226)
core   +1 more source

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle [PDF]

, 2015
Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus.
Magee, DA, Murphy, A., Lohan, AJ, Braud, Martin, Rue-Albrecht, K, Edwards, C.J., Schroeder, Steven, Park, S.D.E., Teasdale, Matthew D., McGettigan, Paul A., Mark, Donoghue, Braud, M, Murphy, Alison, Chamberlain, AT, Bradley, D.G., Chamberlain, Andrew, Liu, Yuan, McGettigan, PA, Lohan, A.J., Spillane, C, Magee, David A., Sonstegard, Tad S., Tai, S, Liu, Y, MacHugh, DE, Murphy, A, School of Earth and Environmental Sciences, Schroeder, S, Tai, Shuaishuai, Bradley, Daniel G., Spillane, Charles, Donaghue, M.T., Park, SD, Braud, M., Loftus, Brendan J., Park, Stephen D E, Chamberlain, Andrew T., Loftus, BJ, MacHugh, David E., Park, Stephen D. E., Bradley, DG, Donoghue, Mark T., Lohan, Amanda J., Teasdale, M.D., Liu, Y., McGettigan, P.A., Teasdale, MD, Magee, D.A., Sonstegard, TS, Donoghue, MT, Edwards, CJ, University of Dublin Trinity College, Rue-Albrecht, Kévin, Chamberlain, A.T., Edwards, Ceiridwen J.   +54 more
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