Results 11 to 20 of about 905,445 (296)

Harmonization of supervised machine learning practices for efficient source attribution of Listeria monocytogenes based on genomic data

BMC Genomics, 2023
Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli, Andrea De Ruvo, Andrea Bucciacchio, Nicola D’Alterio, Cesare Cammà, Adriano Di Pasquale, Nicolas Radomski   +6 more
doaj   +1 more source

Unveiling the immunomodulatory shift: Epithelial-mesenchymal transition Alters immune mechanisms of amniotic epithelial cells

iScience, 2023
Summary: Epithelial-mesenchymal transition (EMT) changes cell phenotype by affecting immune properties of amniotic epithelial cells (AECs). The present study shows how the response to lipopolysaccharide of cells collected pre- (eAECs) and post-EMT (mAECs)
Valeria Di Lollo, Angelo Canciello, Alessia Peserico, Massimiliano Orsini, Valentina Russo, Adrián Cerveró-Varona, Beatrice Dufrusine, Mohammad El Khatib, Valentina Curini, Annunziata Mauro, Paolo Berardinelli, Cathy Tournier, Massimo Ancora, Cesare Cammà, Enrico Dainese, Luana Fiorella Mincarelli, Barbara Barboni   +16 more
doaj   +1 more source

In vitro and in silico parameters for precise cgMLST typing of Listeria monocytogenes

BMC Genomics, 2022
Background Whole genome sequencing analyzed by core genome multi-locus sequence typing (cgMLST) is widely used in surveillance of the pathogenic bacteria Listeria monocytogenes.
Federica Palma, Iolanda Mangone, Anna Janowicz, Alexandra Moura, Alexandra Chiaverini, Marina Torresi, Giuliano Garofolo, Alexis Criscuolo, Sylvain Brisse, Adriano Di Pasquale, Cesare Cammà, Nicolas Radomski   +11 more
doaj   +1 more source

Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease [PDF]

, 2013
Copyright: © 2013 Eyre et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Baines, Simon D., Chilton, Caroline H., Crook, Derrick W., Eyre, David W., Fawley, Warren N., Freeman, Jane, Griffiths, David, Peto, Tim E. A., Vaughan, Alison, Walker, A. Sarah, Wilcox, Mark H.   +10 more
core   +9 more sources

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
doaj   +1 more source

Advances on whole genome sequencing in Triticeae

浙江大学学报. 农业与生命科学版, 2023
The Triticeae provides the important cereal crops, such as wheat, barley, and rye, which produces approximately 9×108 t annually, accounting for about 30% of the total global cereal production. However, Triticeae genomes are relatively difficult to be de
KUANG Liuhui, LI Qi, ZHANG Guoping
doaj   +1 more source

A pipeline for sample tagging of whole genome bisulfite sequencing data using genotypes of whole genome sequencing

BMC Genomics, 2023
Background In large-scale high-throughput sequencing projects and biobank construction, sample tagging is essential to prevent sample mix-ups. Despite the availability of fingerprint panels for DNA data, little research has been conducted on sample ...
Zhe Xu, Si Cheng, Xin Qiu, Xiaoqi Wang, Qiuwen Hu, Yanfeng Shi, Yang Liu, Jinxi Lin, Jichao Tian, Yongfei Peng, Yong Jiang, Yadong Yang, Jianwei Ye, Yilong Wang, Xia Meng, Zixiao Li, Hao Li, Yongjun Wang   +17 more
doaj   +1 more source

Development and Validation of Clinical Whole-Exome and Whole-Genome Sequencing for Detection of Germline Variants in Inherited Disease [PDF]

, 2017
Context.-With the decrease in the cost of sequencing, the clinical testing paradigm has shifted from single gene to gene panel and now whole-exome and whole-genome sequencing.
Ferreira-Gonzalez, Andrea, Hegde, Madhuri, Mao, Rong, Santani, Avni, Voelkerding, Karl V., Weck, Karen E.   +5 more
core   +3 more sources

Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi. [PDF]

, 2018
Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation.
Fookes, Maria, Ghinai, Rosanna, Mabey, David CW, Marks, Michael, Sarkodie, Yaw-Adu, Sokana, Oliver, Solomon, Anthony W, Thomson, Nicholas R, Wagner, Josef   +8 more
core   +1 more source

Whole-Genome Sequencing in Cancer [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Genome sequencing of cancer has fundamentally advanced our understanding of the underlying biology of this disease, and more recently has provided approaches to characterize and monitor tumors in the clinic, guiding and evaluating treatment. Although cancer research is relying more on whole-genome characterization, the clinical application of genomics ...
Eric Y, Zhao, Martin, Jones, Steven J M, Jones   +2 more
openaire   +2 more sources