Results 101 to 110 of about 2,954,248 (364)

Comparison of a full-spectrum multi-analyte clinical analyser with six reference instruments using canine and feline blood samples

Veterinární Medicína, 2017
In this study, we report the characterisation of a novel centrifugation and spectrum-integrated veterinary clinical analyser, the AmiShieldTM, which has been developed for the multiplex measurement of biochemical, electrolyte and immunoassay parameters ...
C.S. Lin, G.H. Chiang, C.H. Liu, H.C. Tsai, C.C. Yang, K. Chen, S.K. Huang, T.L. Cheng, C.C. Chou   +8 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

A novel optical assay system for bilirubin concentration measurement in whole blood [PDF]

IEEE Transactions on Biomedical Engineering 69.2 (2021): 983-990
As a biomarker for liver disease, bilirubin has been utilized in prognostic scoring systems for cirrhosis. While laboratory-based methods are used to determine bilirubin levels in clinical settings, they do not readily lend themselves to applications outside of hospitals. Consequently, bilirubin monitoring for cirrhotic patients is often performed only
arxiv   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Development of a method for measuring blood coagulation using superparamagnetic iron oxide nanoparticles and an alternating magnetic field [PDF]

arXiv, 2016
We developed a method for measuring blood coagulation using superparamagnetic iron oxide nanoparticles (SPIONs) and an alternating magnetic field (AMF). The 3rd and 5th harmonic signals from SPIONs mixed with blood induced by AMF were detected using a gradiometer coil.
arxiv  

On the Modelling and Numerical Simulation of Non-Newtonian Blood Flow in an Aneurysm [PDF]

arXiv, 2020
Cardiovascular diseases, specifically cerebral aneurysms, represent a major cause of morbidity and mortality, having a significant impact on the cost and overall status of health care. In the present work, we employ a haemorheological blood model originally proposed by Owens to investigate the haemodynamics of blood flow through an aneurytic channel ...
arxiv  

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology. [PDF]

, 2016
Circulating tumor cells (CTCs) are emerging as rare but clinically significant non-invasive cellular biomarkers for cancer patient prognosis, treatment selection, and treatment monitoring.
Che, James, Dhar, Manjima, Di Carlo, Dino, Garon, Edward B, Goldman, Jonathan, Heirich, Kyra, Jeffrey, Stefanie S, Kulkarni, Rajan P, Matsumoto, Melissa, Pegram, Mark D, Rao, Jianyu, Renier, Corinne, Sheth, Shruti, Sledge, George W, Sollier, Elodie, Yu, Victor   +15 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]

, 2016
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Gnanadesika, Sukanya, Houston, Stephanie A., Kennedy, Simon, Ugusman, Azizah   +3 more
core   +1 more source