Results 111 to 120 of about 3,071,871 (357)

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins

Frontiers in Aging Neuroscience, 2017
As the world's population ages, the age-related cognitive decline presents a great challenge to world's healthcare systems. One of the molecular mechanisms implicated in cognitive ageing is DNA methylation, an epigenetic modification known to be a key ...
Anna Starnawska, Anna Starnawska, Anna Starnawska, Qihua Tan, Qihua Tan, Matt McGue, Matt McGue, Ole Mors, Ole Mors, Ole Mors, Anders D. Børglum, Anders D. Børglum, Anders D. Børglum, Kaare Christensen, Kaare Christensen, Kaare Christensen, Kaare Christensen, Mette Nyegaard, Mette Nyegaard, Mette Nyegaard, Lene Christiansen, Lene Christiansen   +21 more
doaj   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Whole Blood as a Sample Matrix in Homogeneous Time-Resolved Assay—Förster Resonance Energy Transfer-Based Antibody Detection

Diagnostics
The protein-L-utilizing Förster resonance energy transfer (LFRET) assay enables mix-and-read antibody detection, as demonstrated for sera from patients with, e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika virus, and ...
Annika Lintala, Olli Vapalahti, Arttu Nousiainen, Anu Kantele, Jussi Hepojoki   +4 more
doaj   +1 more source

A WHOLE BLOOD OXIMETER [PDF]

Heart, 1957
J. T. Shepherd, R. F. Whelan, I. C. Roddie   +2 more
openaire   +3 more sources

Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]

, 2019
Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary, Chesney, Margaret, Conley, Yvette P, Kober, Kord M, Levine, Jon D, Melisko, Michelle, Miaskowski, Christine, Paul, Steven M, Schumacher, Mark, Topp, Kimberly   +9 more
core  

On the residual reduction of the whole blood, serum and corpuscules¹ [PDF]

, 1930
Richard Ege, Jean Roche
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

The Bactericidal Action of the Whole Blood of Rabbits Following Inoculations of Pneumococcus Bacterins [PDF]

, 1919
George D. Heist, SOLOMON SOLIS-COHEN
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Whole blood filtration. [PDF]

Journal of Clinical Pathology, 1981
E Ernst, John A. Dormandy
openaire   +3 more sources