Results 61 to 70 of about 77,543 (273)

DNA damage in healthy individuals and respiratory patients after treating whole blood in vitro with the bulk and nano forms of NSAIDs

Frontiers in Molecular Biosciences, 2016
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity which affects the inflammatory response. Inflammation is associated with increasing cancer incidence. Pre-clinical and clinical studies have shown that NSAID treatment could cause
Diana Anderson, Mojgan Najafzadeh, Charmaine Normington, Badie Jacob, Mohammad Isreb, Rajendran Gopalan   +5 more
doaj   +1 more source

Novel insights into the immune cell landscape and gene signatures in autism spectrum disorder by bioinformatics and clinical analysis

Frontiers in Immunology, 2023
The pathogenesis of autism spectrum disorder (ASD) is not well understood, especially in terms of immunity and inflammation, and there are currently no early diagnostic or treatment methods. In this study, we obtained six existing Gene Expression Omnibus
Hongwei Li, Yiran Xu, Yiran Xu, Wenhua Li, Lingling Zhang, Xiaoli Zhang, Bingbing Li, Yiwen Chen, Xiaoyang Wang, Xiaoyang Wang, Changlian Zhu, Changlian Zhu   +11 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley   +1 more source

A Quantitative Immunochromatography Assay of Whole Blood Samples for Antigen-specific IgE—A New Method for Point of Care Testing for Allergens—

Allergology International, 2005
Background: The development of an inexpensive point-of-care testing system for antigen-specific IgE is greatly needed. We, therefore, tried to develop a quantitative enzyme immunochromatography assay system for antigen-specific IgE in fresh whole blood ...
Tetsuya Ono, Kazuyuki Sugiyama, Takashi Kuroda, Masahide Kawamura, Shinsuke Arao, Hideo Nariuchi   +5 more
doaj   +1 more source

Infusion therapy as an important element of anesthetic strategy for the wounded with hemorrhagic shock

Медицина неотложных состояний, 2022
Hemorrhagic shock remains the main cause of death of the wounded in all wars and military conflicts. A key aspect in modern anesthetic strategy for the wounded with hemorrhagic shock is the strategy of a balanced infusion therapy.
O.V. Raboshchuk, G.P. Khytriy, V.M. Moshkivskyi, M.A. Khodakivskyi   +3 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

One-Step Detection of Vancomycin in Whole Blood Using the Lateral Flow Immunoassay

Biosensors
Vancomycin (VAN) is an effective antibiotic against Gram-positive bacteria and the first-line therapy to prevent and treat methicillin-resistant Staphylococcus aureus (MRSA) and severe infections.
Yugyung Jung, Seonjong Kim, Min-Gon Kim, Young-Eun Lee, Myung-Geun Shin, Sung Yang   +5 more
doaj   +1 more source

Combined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy alone

Frontiers in Immunology, 2012
Periodic assessment of gene expression for diagnosis and monitoring in rheumatoid arthritis (RA) may provide a readily available and useful method to detect subclinical disease progression and follow responses to therapy with disease modifying anti ...
Carl K Edwards, Carl K Edwards, Julie Schwartz Green, Hans-Dieter eVolk, Michael eSchiff, Brian eKotzin, Hiroaki eMitsuya, Tatsuya eKawaguchi, Ken-Mei eSakata, John eCheronis, David eTrollinger, Danute eBankaitis-Davis, Charles A Dinarello, David A Norris, David A Norris, Michael P Bevilacqua, Mayumi eFujita, Mayumi eFujita, Gerd-Rudiger eBermester   +18 more
doaj   +1 more source