Results 1 to 10 of about 40,044 (70)

SARS-CoV-2 surveillance in Italy through phylogenomic inferences based on Hamming distances derived from pan-SNPs, -MNPs and -InDels

open access: yesBMC Genomics, 2021
Background Faced with the ongoing global pandemic of coronavirus disease, the ‘National Reference Centre for Whole Genome Sequencing of microbial pathogens: database and bioinformatic analysis’ (GENPAT) formally established at the ‘Istituto ...
Adriano Di Pasquale   +5 more
doaj   +1 more source

Harmonization of supervised machine learning practices for efficient source attribution of Listeria monocytogenes based on genomic data

open access: yesBMC Genomics, 2023
Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli   +6 more
doaj   +1 more source

In vitro and in silico parameters for precise cgMLST typing of Listeria monocytogenes

open access: yesBMC Genomics, 2022
Background Whole genome sequencing analyzed by core genome multi-locus sequence typing (cgMLST) is widely used in surveillance of the pathogenic bacteria Listeria monocytogenes.
Federica Palma   +11 more
doaj   +1 more source

Unveiling the immunomodulatory shift: Epithelial-mesenchymal transition Alters immune mechanisms of amniotic epithelial cells

open access: yesiScience, 2023
Summary: Epithelial-mesenchymal transition (EMT) changes cell phenotype by affecting immune properties of amniotic epithelial cells (AECs). The present study shows how the response to lipopolysaccharide of cells collected pre- (eAECs) and post-EMT (mAECs)
Valeria Di Lollo   +16 more
doaj   +1 more source

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

open access: yesMicroorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini   +9 more
doaj   +1 more source

Genomic data of an environmental Escherichia coli isolate shows high resemblance to E. coli K-12 reference strain MG1655

open access: yesData in Brief, 2021
Escherichia coli species exhibits a high genomic diversification from evolution, mobile genetic elements and recombination. An environmental E. coli isolate, ‘JHI_5025’ from a crop trial appeared to be clonally related to the historical reference isolate
Nicola Holden
doaj   +1 more source

Whole genome sequencing of elite athletes

open access: yesBiology of Sport, 2020
Whole genome sequencing (WGS) has great potential to explore all possible DNA variants associated with physical performance, psychological traits and health conditions of athletes.
Eugenia A. Boulygina   +14 more
doaj   +1 more source

Performance Characteristics of Next-Generation Sequencing for the Detection of Antimicrobial Resistance Determinants in Escherichia coli Genomes and Metagenomes

open access: yesmSystems, 2022
Short-read sequencing can provide detection of multiple genomic determinants of antimicrobial resistance from single bacterial genomes and metagenomic samples. Despite its increasing application in human, animal, and environmental microbiology, including
Ashley M. Rooney   +8 more
doaj   +1 more source

HLA Association with Drug-Induced Adverse Reactions

open access: yesJournal of Immunology Research, 2017
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan   +6 more
doaj   +1 more source

Genomic and Biocontrol Potential of the Crude Lipopeptide by Streptomyces bikiniensis HD-087 Against Magnaporthe oryzae

open access: yesFrontiers in Microbiology, 2022
Rice blast caused by Magnaporthe oryzae is one of the most destructive plant diseases. The secondary metabolites of Streptomyces have potential as biological control agents against M. oryzae.
Wei Liu   +15 more
doaj   +1 more source

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