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Whole-genome duplication events of four palms.
, 2015 (A) The distribution of synonymous substitution rate (Ks) of the paralogs is displayed in red and blue for N. fruticans and P. dactylifera, respectively. Peaks I and II indicated two whole-genome duplication events in both species. The yellow bars showed
Zhang Zhang (14172) +5 more
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Localization of an accessory helicase at the replisome is critical in sustaining efficient genome duplication [PDF]
, 2010 © The Author(s) 2010. Published by Oxford University PressGenome duplication requires accessory helicases to displace proteins ahead of advancing replication forks.
Lloyd, RG +11 more
core +1 more source
Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
The house spider genome reveals an ancient whole-genome duplication during arachnid evolution
BMC Biology, 2017 Background The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate
Evelyn E. Schwager +54 more
doaj +1 more source
Finding Evidence for Whole Genome Duplications: A Reappraisal [PDF]
Molecular Plant, 2019 Zwaenepoel, Arthur +3 more
openaire +3 more sources
Reply to: 'Subfunctionalization versus neofunctionalization after whole-genome duplication'.
, 2018 Reply to: 'Subfunctionalization versus neofunctionalization after whole-genome duplication'
Guiguen, Yann +7 more
core +1 more source
Advanced Science, EarlyView.Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
Whole Genome Duplications and a ‘Function’ for Junk DNA? Facts and Hypotheses
PLoS ONE, 2009 The lack of correlation between genome size and organismal complexity is understood in terms of the massive presence of repetitive and non-coding DNA. This non-coding subgenome has long been called "junk" DNA. However, it might have important functions.
Veitia, Reiner A., Bottani, Samuel
openaire +5 more sources
, 2019 Novel teleost whole-genome sequences for studying genome evolution after whole genome duplication and sex determination.
Guiguen, Yann
core
Advanced Science, EarlyView.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source