The Combinatorics of Tandem Duplication Trees [PDF]
Systematic Biology, 2003 We developed a recurrence relation that counts the number of tandem duplication trees (either rooted or unrooted) that are consistent with a set of n tandemly repeated sequences generated under the standard unequal recombination (or crossover) model of tandem duplications.
Olivier Gascuel +2 more
exaly +4 more sources
A Rare Case of Nasal Sarcoma with BCOR Internal Tandem Duplication Showing Complete Pathologic Response to the VDC-IE Chemotherapy Protocol [PDF]
Case Reports in Oncological Medicine, 2023 Sarcoma with BCOR genetic alteration is an exceptionally rare and emerging subtype of sarcoma. It is categorized into two types: BCOR-related gene fusions such as BCOR::CCNB3 sarcomas and other BCOR-rearranged sarcoma and sarcomas with internal tandem ...
Samer Salah +10 more
doaj +2 more sources
Mechanisms of tandem duplication in the cancer genome. [PDF]
DNA Repair (Amst)Tandem duplications (TD) are among the most frequent type of structural variant (SV) in the cancer genome. They are characterized by a single breakpoint junction that defines the boundaries and the size of the duplicated segment. Cancer-associated TDs often increase oncogene copy number or disrupt tumor suppressor gene function, and thus have important
Scully R +4 more
europepmc +3 more sources
Detecting long tandem duplications in genomic sequences [PDF]
BMC Bioinformatics, 2012 Background Detecting duplication segments within completely sequenced genomes provides valuable information to address genome evolution and in particular the important question of the emergence of novel functions.
Audemard Eric +2 more
doaj +6 more sources
An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing [PDF]
Experimental Biology and MedicineAccurate identifying internal tandem duplication (ITD) mutation is indispensable for diagnosis and prognosis of acute myeloid leukemia (AML) patients, but specialized full-size detection tools are lacking. Therefore, we aimed to develop a reliable system
Li-Li Zhang +7 more
doaj +2 more sources
The impact of tandem duplication on gene evolution in Solanaceae species
Journal of Integrative Agriculture, 2022 Whole genome duplication (WGD) and tandem duplication (TD) are important modes of gene amplification and functional innovation, and they are common in plant genome evolution.
Jianbin Hu, Feng Cheng
exaly +3 more sources
Construction of tandem duplication correcting codes [PDF]
IET Communications, 2019 Tandem duplication (TD) errors occur when data is stored in the DNA of living organisms. The construction of codes to correct these errors was previously considered. A method was proposed to construct codes for TD errors of length at most k , , based ...
Mohamadbagher Zeraatpisheh +2 more
exaly +2 more sources
Computing the Tandem Duplication Distance is NP-Hard
SIAM Journal on Discrete Mathematics, 2022 © SIAM. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing help@openaccessbutton.org.
Manuel Lafond, Binhai Zhu, Peng Zou
exaly +3 more sources
An Irak1-Mecp2 tandem duplication mouse model for the study of MECP2 duplication syndrome [PDF]
Disease Models & MechanismsEleonora Maino +13 more
doaj +2 more sources
Genotyping inversions and tandem duplications [PDF]
Bioinformatics, 2017 Abstract Motivation Next Generation Sequencing (NGS) has enabled studying structural genomic variants (SVs) such as duplications and inversions in large cohorts. SVs have been shown to play important roles in multiple diseases, including cancer.
J. Ebler (Jana) +2 more
openaire +5 more sources