The Combinatorics of Tandem Duplication Trees [PDF]
Systematic Biology, 2003 We developed a recurrence relation that counts the number of tandem duplication trees (either rooted or unrooted) that are consistent with a set of n tandemly repeated sequences generated under the standard unequal recombination (or crossover) model of tandem duplications.
Mike Steel +2 more
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The combinatorics of tandem duplication [PDF]
Discrete Applied Mathematics, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Luca Penso Dolfin +2 more
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Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae [PDF]
Advanced ScienceTandem duplication of tailoring enzymes allows evolutionary innovation that diversifies plant specialized metabolism. Here, we present an interesting example of how tandem duplicated UDP‐glycosyltransferases undergo neofunctionalization and shape the ...
Guangyi Wang +13 more
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A Rare Case of Nasal Sarcoma with BCOR Internal Tandem Duplication Showing Complete Pathologic Response to the VDC-IE Chemotherapy Protocol [PDF]
Case Reports in Oncological Medicine, 2023 Sarcoma with BCOR genetic alteration is an exceptionally rare and emerging subtype of sarcoma. It is categorized into two types: BCOR-related gene fusions such as BCOR::CCNB3 sarcomas and other BCOR-rearranged sarcoma and sarcomas with internal tandem ...
Samer Salah +10 more
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On Counting Tandem Duplication Trees [PDF]
Molecular Biology and Evolution, 2004 IntroductionLarge genomes are full of repeated DNA sequences.It was estimated that over half of the human DNA consistsof repeated sequences (Baltimore 2001; Eichler 2001;Leem et al. 2002). Tandem duplication is one of theimportant evolutionary mechanisms for producing re-peated DNA sequences, in which the copies that may ormay not contain genes are ...
Louxin Zhang, Jialiang Yang
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Detecting long tandem duplications in genomic sequences [PDF]
BMC Bioinformatics, 2012 Background Detecting duplication segments within completely sequenced genomes provides valuable information to address genome evolution and in particular the important question of the emergence of novel functions.
Audemard Eric +2 more
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Mechanisms of tandem duplication in the cancer genome. [PDF]
DNA Repair (Amst)Tandem duplications (TD) are among the most frequent type of structural variant (SV) in the cancer genome. They are characterized by a single breakpoint junction that defines the boundaries and the size of the duplicated segment. Cancer-associated TDs often increase oncogene copy number or disrupt tumor suppressor gene function, and thus have important
Scully R +4 more
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Computing the Tandem Duplication Distance is NP-Hard
SIAM Journal on Discrete Mathematics, 2022 © SIAM. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing help@openaccessbutton.org.
Binhai Zhu, Manuel Lafond
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An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing [PDF]
Experimental Biology and MedicineAccurate identifying internal tandem duplication (ITD) mutation is indispensable for diagnosis and prognosis of acute myeloid leukemia (AML) patients, but specialized full-size detection tools are lacking. Therefore, we aimed to develop a reliable system
Li-Li Zhang +7 more
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The impact of tandem duplication on gene evolution in Solanaceae species
Journal of Integrative Agriculture, 2022 Whole genome duplication (WGD) and tandem duplication (TD) are important modes of gene amplification and functional innovation, and they are common in plant genome evolution.
Jianbin Hu, Feng Cheng
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