Results 21 to 30 of about 52,373 (299)
Haematologica, 2011 Background Fms-like tyrosine kinase-3 (FLT3) gene mutations are frequent in acute promyelocytic leukemia but their prognostic value is not well established.Design and Methods We evaluated FLT3-internal tandem duplication and FLT3-D835 mutations in ...
Eva Barragán +19 more
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Characterization and evolution of microRNA genes derived from repetitive elements and duplication events in plants. [PDF]
PLoS ONE, 2012 MicroRNAs (miRNAs) are a major class of small non-coding RNAs that act as negative regulators at the post-transcriptional level in animals and plants. In this study, all known miRNAs in four plant species (Arabidopsis thaliana, Populus trichocarpa, Oryza
Jie Sun +3 more
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The shape of human gene family phylogenies [PDF]
, 2006 Background: The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process. Previous studies have focused
James A Cotton +5 more
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Intron gain by tandem genomic duplication: a novel case in a potato gene encoding RNA-dependent RNA polymerase [PDF]
PeerJ, 2016 The origin and subsequent accumulation of spliceosomal introns are prominent events in the evolution of eukaryotic gene structure. However, the mechanisms underlying intron gain remain unclear because there are few proven cases of recently gained introns.
Ming-Yue Ma, Xin-Ran Lan, Deng-Ke Niu
doaj +2 more sources
Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]
, 2012 Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian +93 more
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Haematologica, 2018 KMT2A partial tandem duplication occurs in approximately 5–10% of patients with acute myeloid leukemia and is associated with adverse prognosis. KMT2A wild type is epigenetically silenced in KMT2A partial tandem duplication; re-expression can be induced ...
Alice S. Mims +20 more
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Evolution of Vertebrate Adam Genes; Duplication of Testicular Adams from Ancient Adam9/9-like Loci. [PDF]
PLoS ONE, 2015 Members of the disintegrin metalloproteinase (ADAM) family have important functions in regulating cell-cell and cell-matrix interactions as well as cell signaling.
Harinath Bahudhanapati +2 more
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Plants, 2023 Wheat (Triticum aestivum L.) is a staple food crop that provides 20% of total human calorie consumption. Gene duplication has been considered to play an important role in evolution by providing new genetic resources.
Licao Cui +5 more
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STIL binding to Polo-box 3 of PLK4 regulates centriole duplication [PDF]
, 2015 Polo-like kinases (PLK) are eukaryotic regulators of cell cycle progression, mitosis and cytokinesis; PLK4 is a master regulator of centriole duplication.
Timm Maier +15 more
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The Tandem Duplication Distance Is NP-Hard [PDF]
, 2020 In computational biology, tandem duplication is an important biological phenomenon which can occur either at the genome or at the DNA level. A tandem duplication takes a copy of a genome segment and inserts it right after the segment - this can be ...
Lafond, Manuel, Zou, Peng, Zhu, Binhai
core +1 more source