Results 111 to 120 of about 86,476 (288)
Genetic variation in the chicken genome: insights in selection
, 2011 The chicken currently provides more than a quarter of the meat and nearly all eggs produced worldwide. For future improvements in production traits and animal welfare as well as to address future consumer demands it is necessary to understand the ...Elferink, M.G.core Multi-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis [PDF]
, 2010 A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo).Kent M Reed, Zhang, Liqing, Zhang Hong-Bin, Kim, Heebal, Rami A Dalloul, Langenberger, D., Scheuring, C., Evans, Clive, Crooijmans, R. P. M. A., Lee, Mi-Kyung, Lee, Taeheon, Kim, H., Evans, C., Nefedov Mikhail, Mane, Shrinivasrao, Frederickson, K. M., Crooijmans, Richard P. M. A., Williams, K. P., Marz, M., Liqing Zhang, Paul Flicek, Dodgson, J. B., David Langenberger, Smith Jacqueline, Dodgson, J. B., Flicek, Paul, Dong, J. J., Jiang, A., Kim, K. W., Zhang Yang, Kim, H., Manja Marz, Long, J. A., Williams, Kelly P., Schatz Michael C., Julie A. Long, Raineri Emanuele, Folkerts, O., Otto Folkerts, Zhang, H.-B., McElroy, A. P., Zhang, L., Delany, Mary E., Long, Julie A., Kelly P. Williams, McElroy Audrey P., Paton, I. R., Beal Kathryn, de Jong, P., Vilella, A. J., Yorke, J. A., Vilella Albert J., Salzberg, Steven L., Harkins Tim T., Megens, H.-J., Kim Sungwon, Crasta Oswald, Burt, David W., Bouffard Pascal, Schroeder, S., Albert J. Vilella, Burt, D. W., Liliana Florea, Mane Shrinivasrao, Carl J. Schmidt, Modise, Thero, Harkins, T. T., Jacqueline Smith, Frederickson, Karin M., Kristal Cooper, Stadler Peter F., Martien A. M. Groenen, Steven L. Salzberg, van Tassell, C. P., Smith, E. J., Blomberg, L. A., Modise, T., Tafer, Hakim, Schmidt, C. J., William S Payne, Dong, Jennifer J., Florea Liliana, Vilella, A. J., Notredame, C., Lee, M. K., Smith, J., Kathryn Beal, Jiang, A., Bouffard, Pascal, Geo Pertea, Mi-Kyung Lee, Mane, S., Roberts, Richard J., Delany, M. E., Jerry B. Dodgson, Schmidt, Carl J., Pertea, Geo, Searle Stephen M. J., Williams, K. P., Frederickson Karin M., Beal, K., Tim T Harkins, Lee, T., Langenberger, David, Searle, S. M. J., Ruffier, M., Puiu, D., Dalloul, R. A., Van Tassell, C. P., Schatz, M. C., Julie A Long, Jennifer J Dong, Raineri, E., Modise Thero, Long Julie A., Reed, Kent M., De, Supriyo, Oswald Crasta, Zimin, Aleksey V., Folkerts, O., Zhang, Y., Schroeder Steven, Roger A Coulombe, Hoffmann Steve, Crasta, Oswald, McElroy, Audrey P., Tu, Zhijian Jake, Florea, L., Magali Ruffier, de, J. P., Curtis P. Van Tassell, Williams Kelly P., William S. Payne, Megens, H. J., Zhang, X., Bouffard, P., James A Yorke, Kaiser, Pete, Daniela Puiu, Stephen M. J. Searle, Modise, T., Notredame Cédric, Groenen, M. A. M., Hoffmann, Steve, Notredame, C��dric, Ruffier Magali, Taeheon Lee, Guillaume Marcais, Evans Clive, Le Ann Blomberg, Qioa, Dan, Herrero Javier, Zhang Liqing, Crooijmans, R. P., Kim, S., Evans, C., Prickett, Dennis, Groenen, M. A., Cooper, K., Tu, Z. J., Dalloul, R.A., De Supriyo, Kaiser, P., Schmidt, C. J., Van Tassell Curtis P., Tafer, H., Megens, Hendrik-Jan, Mane, Shrinivasrao P., Tafer, H., Marcais, G., Xiaojun Zhang, Crasta, O., Kyu-Won Kim, Dodgson Jerry B., Aleksey V. Zimin, Reed, K. M., Steve Hoffmann, Tu, Zhijian (Jake), Dalloul, Rami A., Ann Blomberg Le, Hoffmann, S., Zhang, Yang, David W Burt, Kent M. Reed, Pieter de Jong, Aslam, Luqman, Marz, M., Groenen, Martien A. M., Michael C Schatz, Zhijian Jake Tu, Burt David W., Pascal Bouffard, Pertea Geo, Richard P M A Crooijmans, Audrey P. McElroy, David W. Burt, Sonstegard, T. S., Marcais, G., Hakim Tafer, Smith, J., Zhang, H. B., Ruffier, Magali, Mikhail Nefedov, Albert J Vilella, Megens Hendrik-Jan, Clive Evans, Hendrik-Jan Megens, Kaiser Pete, Dennis Prickett, Puiu Daniela, Dan Qioa, Schroeder, S., Zhang, Hong-Bin, Zhang, Xiaojun, Audrey P McElroy, Zimin Aleksey V., Vilella, Albert J., Groenen, M. A. M., Martien A M Groenen, Coulombe, R. A., Supriyo De, Scheuring, C., Qioa, D., Van, T. C. P., Nefedov, M., Kim, K.-W., de Jong Pieter, McElroy, A. P., Folkerts, Otto, Yorke James A., Harkins, Tim T., Rami A. Dalloul, Zhijian (Jake) Tu, Lee Taeheon, Crooijmans, R.P.M.A., Searle, S. M., Megens, H. J., Edward J. Smith, Paton Ian R., Salzberg, S. L., Aleksey V Zimin, Cooper Kristal, Ian R. Paton, Emanuele Raineri, Langenberger David, Tu Zhijian (Jake), Long, J. A., Qioa, D., Coulombe, R. A., Pete Kaiser, Aslam Luqman, Mane, S., Delany, M. E., Schatz, M. C., Sonstegard Tad S., Marz, Manja, Payne, William S., Carl J Schmidt, Andrew Jiang, Tu, Z., James A. Yorke, Long, J.A., Kelly P Williams, Lee, T., Edward J Smith, Notredame, Cédric, Stadler, P. F., Aslam, L., Prickett Dennis, Zimin, A. V., Herrero, J., Searle, S. M. J., Burt, D. W., Luqman Aslam, Crasta, O., Langenberger, D., Kaiser, P., Stadler, P. F., Van Tassell, Curtis P., Schmidt Carl J., Sonstegard, Tad S., Marz Manja, Lee, M. K., Puiu, Daniela, Marcais Guillaume, Crooijmans Richard P. M. A., Blomberg, Le Ann, Groenen Martien A. M., de Jong, P., Ruffier, M., Tad S. Sonstegard, Dalloul, R. A., Jiang Andrew, Frederickson, K. M., Florea, Liliana, Aslam, M.L., Smith Edward J., de Jong, Pieter, Cédric Notredame, Kim, K. W., Searle, Stephen M. J., Smith, Jacqueline, Harkins, T. T., Smith, Edward J., Karin M Frederickson, Chantel Scheuring, Marcais, Guillaume, Dalloul Rami A., Curtis P Van Tassell, Kim, Kyu-Won, Kim, S., Mary E Delany, Hong-Bin Zhang, Michael C. Schatz, Scheuring, Chantel, Kim Kyu-Won, Jiang, Andrew, Payne, W. S., Folkerts Otto, Zhang, H. B., Zimin, A. V., Schroeder, Steven, Yorke, J. A., Megens, H.J.W.C., Heebal Kim, Payne, W. S., Ann Blomberg, Le, Beal, K., Smith, Jacqueline; id_orcid, Puiu, D., Reed, K. M., Crooijmans, R. P. M. A., Qioa Dan, Notredame, C., Pertea, G., Stephen M J Searle, Zhang Xiaojun, Prickett, D., Flicek, P., Salzberg, S. L., Karin M. Frederickson, Florea, L., Coulombe, Roger A., Smith, E. J., Delany Mary E., Scheuring Chantel, Sungwon Kim, Salzberg Steven L., Aslam, L., Jerry B Dodgson, Yang Zhang, Yorke, James A., Raineri, Emanuele, Paton, I. R., Bouffard, P., Tafer Hakim, Cooper, K., Dong, J. J., Nefedov, Mikhail, Kim Heebal, Cooper, Kristal, Roger A. Coulombe, Tim T. Harkins, Tad S Sonstegard, De, S., Nefedov, M., Herrero, Javier, Blomberg, L. A., Lee, M.-K., Mary E. Delany, Raineri, E., Zhang, L., Hoffmann, S., De, S., Peter F Stadler, Kim, Sungwon, Zhang, X., Thero Modise, Beal, Kathryn, Sonstegard, T. S., Richard P. M. A. Crooijmans, Prickett, D., Steven Schroeder, Payne William S., Jennifer J. Dong, Groenen, M., Ann Blomberg, L., Lee Mi-Kyung, Zhang, Y., Flicek, P., Zimin, A.V., Dong Jennifer J., Schatz, Michael C., Coulombe Roger A., Peter F. Stadler, Flicek Paul, Javier Herrero, Paton, Ian R., Herrero, J., Ian R Paton, Dodgson, Jerry B., Steven L Salzberg, Shrinivasrao Mane, Stadler, Peter F., Pertea, G., Reed Kent M. +405 morecore +1 more sourcePaternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding +22 morewiley +1 more sourceAGAPE (Automated Genome Analysis PipelinE) for Pan-Genome Analysis of Saccharomyces cerevisiae
, 2015 The characterization and public release of genome sequences from thousands of organ- isms is expanding the scope for genetic variation studies. However, understanding the
phenotypic consequences of genetic variation remains a challenge in eukaryotes due Kisurb Choe, Benjamin J. A. Dickins (703565), Stacia Engel (703566), Barbara Dunn, Barbara Dunn (393141), Janos Demeter (5547), Song Giltae, Giltae Song, Dunn Barbara, Jennifer Gallagher, Cherry, JM, Choe, K, Dickins Benjamin J. A., J. Michael Cherry (5627), Demeter, J, Janos Demeter, Dickins, BJA, Snyder, M, Giltae Song (703564), Song, G, Dunn, B, Benjamin J A Dickins, J Michael Cherry, Gallagher, J, Stacia Engel, Engel, S, Demeter Janos, Michael Snyder, Engel Stacia, Cherry J. Michael +29 morecore +1 more sourceDOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation
Advanced Science, EarlyView.DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng +11 morewiley +1 more sourceEnhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao +8 morewiley +1 more sourceStudying Whole-Genome Duplication Using Experimental Evolution of Chlamydomonas
, 2023 In this chapter, we present the use of Chlamydomonas reinhardtii in experiments designed to study the evolutionary impacts of whole genome duplication. We shortly introduce the algal species and depict why it is an excellent model for experimental evolution.Bafort, Quinten, Prost, Lucas, Aydogdu, Eylem, Van de Vloet, Antoine, Casteleyn, Griet, Van de Peer, Yves, De Clerck, Olivier +6 moreopenaire +3 more sources3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species
Advanced Science, EarlyView.ABSTRACT
Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu +11 morewiley +1 more source
