Results 91 to 100 of about 2,879,199 (292)

The chromosome-level genome of Eucommia ulmoides provides insights into sex differentiation and α-linolenic acid biosynthesis

Frontiers in Plant Science, 2023
Eucommia ulmoides Oliver is a typical dioecious plant endemic to China that has great medicinal and economic value. Here, we report a high-quality chromosome-level female genome of E. ulmoides obtained by PacBio and Hi-C technologies.
Qingxin Du, Qingxin Du, Qingxin Du, Zixian Wu, Panfeng Liu, Panfeng Liu, Panfeng Liu, Jun Qing, Jun Qing, Jun Qing, Feng He, Feng He, Feng He, Lanying Du, Lanying Du, Lanying Du, Zhiqiang Sun, Zhiqiang Sun, Zhiqiang Sun, Lili Zhu, Hongchu Zheng, Zongyi Sun, Long Yang, Lu Wang, Lu Wang, Lu Wang, Hongyan Du, Hongyan Du, Hongyan Du   +28 more
doaj   +1 more source

Gene-interleaving patterns of synteny in the Saccharomyces cerevisiae genome: are they proof of an ancient genome duplication event?

Biology Direct, 2007
Background Recent comparative genomic studies claim local syntenic gene-interleaving relationships in Ashbya gossypii and Kluyveromyces waltii are compelling evidence for an ancient whole-genome duplication event in Saccharomyces cerevisiae. We here test,
Sun Feng-Jie, LeDuc Richard, Ruedi Elizabeth A, Martin Nicolas, Caetano-Anollés Gustavo   +4 more
doaj   +1 more source

Supplemental data for: "Effect of whole-genome duplication on the evolutionary rescue of sterile hybrid monkeyflowers"

, 2020
Hybridisation is a creative evolutionary force, increasing genomic diversity, and facilitating adaptation and even speciation. Hybrids often face significant challenges to become established, including reduced fertility arising from genomic ...
De Storme, Nico, Meeus, Sofie, Geelen, Danny, Šemberová, Kristýna, Vallejo-Marin, Mario   +4 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Pigmentation Pathway Evolution after Whole-Genome Duplication in Fish [PDF]

Genome Biology and Evolution, 2009
Whole-genome duplications (WGDs) have occurred repeatedly in the vertebrate lineage, but their evolutionary significance for phenotypic evolution remains elusive. Here, we have investigated the impact of the fish-specific genome duplication (FSGD) on the evolution of pigmentation pathways in teleost fishes.
Braasch, Ingo, Brunet, Frédéric, Volff, Jean-Nicolas, Schartl, Manfred   +3 more
openaire   +4 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparative Inference of Duplicated Genes Produced by Polyploidization in Soybean Genome

International Journal of Genomics, 2013
Soybean (Glycine max) is one of the most important crop plants for providing protein and oil. It is important to investigate soybean genome for its economic and scientific value. Polyploidy is a widespread and recursive phenomenon during plant evolution,
Yanmei Yang, Jinpeng Wang, Jianyong Di
doaj   +1 more source

The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication [PDF]

, 2018
Whole-genome duplication (WGD) has been a major evolutionary driver of increased genomic complexity in vertebrates. One such event occurred in the salmonid family ∼80 Ma (Ss4R) giving rise to a plethora of structural and regulatory duplicate-driven ...
Leif Asbjørn Vøllestad, Sissel Jentoft, Varadharajan, Srinidhi, Kjetill S Jakobsen, Sandve, Simen R., Mulugeta, Teshome D., Teshome D Mulugeta, Jakobsen, Kjetill Sigurd, Mulugeta, Teshome Dagne, Hvidsten, Torgeir R.,, Sandve, Simen Rød, Simen R Sandve, Gillard, Gareth B., Hvidsten, Torgeir R., Torgeir R Hvidsten, Gillard, Gareth Benjamin, Srinidhi Varadharajan, Ole K Tørresen, Tørresen, Ole K., Gareth B Gillard, Vøllestad, Leif Asbjørn, Jentoft, Sissel, Nederbragt, Alexander J., Alexander J Nederbragt, Jakobsen, Kjetill S., Nederbragt, Alexander Johan, Lien, Sigbjørn, Hvidsten, Torgeir Rhoden, Sigbjørn Lien   +28 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Nature Communications, 2021
Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in
Yifei Liu, Bo Wang, Shaohua Shu, Zheng Li, Chi Song, Di Liu, Yan Niu, Jinxin Liu, Jingjing Zhang, Heping Liu, Zhigang Hu, Bisheng Huang, Xiuyu Liu, Wei Liu, Liping Jiang, Mohammad Murtaza Alami, Yuxin Zhou, Yutao Ma, Xiangxiang He, Yicheng Yang, Tianyuan Zhang, Hui Hu, Michael S. Barker, Shilin Chen, Xuekui Wang, Jing Nie   +25 more
doaj   +1 more source