Results 151 to 160 of about 155,374 (249)

Whole Genome Duplication in the Genomics Era: The Hidden Gems in Invertebrates? [PDF]

Genome Biol Evol
Au HM, Nong W, Hui JHL.
europepmc   +1 more source

Parallel Nonfunctionalization of CK1δ/ε Kinase Ohnologs Following a Whole-Genome Duplication Event. [PDF]

Mol Biol Evol, 2023
Evans-Yamamoto D, Dubé AK, Saha G, Plante S, Bradley D, Gagnon-Arsenault I, Landry CR.   +6 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Whole-genome duplication increases genetic diversity and load in outcrossing Arabidopsis arenosa. [PDF]

Proc Natl Acad Sci U S A
Vlček J, Hämälä T, Vives Cobo C, Curran E, Šrámková G, Slotte T, Schmickl R, Yant L, Kolář F.   +8 more
europepmc   +1 more source

Independent rediploidization masks shared whole genome duplication in the sturgeon-paddlefish ancestor. [PDF]

Nat Commun, 2023
Redmond AK, Casey D, Gundappa MK, Macqueen DJ, McLysaght A.   +4 more
europepmc   +1 more source

Molecular characterization of the A52 murine hepatocellular carcinoma cell line

Animal Models and Experimental Medicine, EarlyView.
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman, Eun Jin Sun, Miriam Wankell, Matt A. Field, Ulf Schmitz, Lionel Hebbard   +5 more
wiley   +1 more source

Whole-Genome Sequence of Potamopyrgus antipodarum-A Model System for the Maintenance of Sexual Reproduction-Reveals a Recent Whole-Genome Duplication. [PDF]

Genome Biol Evol
Jalinsky J, McElroy KE, Sharbrough J, Bankers L, Fields PD, Higgins C, Toll C, Boore JL, Logsdon JM, Neiman M.   +9 more
europepmc   +1 more source

Telomere-to-telomere pear (Pyrus pyrifolia) reference genome reveals segmental and whole genome duplication driving genome evolution. [PDF]

Hortic Res, 2023
Sun M, Yao C, Shu Q, He Y, Chen G, Yang G, Xu S, Liu Y, Xue Z, Wu J.   +9 more
europepmc   +1 more source

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

Animal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang, Wei Dai, Jiqiang Liu, Zhengguang Wang   +3 more
wiley   +1 more source

Whole-genome duplication leads to significant but inconsistent changes in climatic niche. [PDF]

Proc Natl Acad Sci U S A
Meirmans PG, Kolář F.
europepmc   +1 more source