Whole-Genome Duplication and Genome Instability in Cancer Cells: Double the Trouble. [PDF]
Int J Mol Sci, 2023 Lau TY, Poon RYC.
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British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg +7 more
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E2F activity determines mitosis versus whole-genome duplication in G2-arrested cells. [PDF]
Nat CommunKim K, Armand J, Kim S, Yang HW.
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An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease. [PDF]
J Dev Biol, 2023 Schvarzstein M +3 more
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Early evolutionary history of the seed
Biological Reviews, EarlyView.ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman +2 more
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Distinct patterns of genome size evolution in each bryophyte lineage are not correlated with whole genome duplication. [PDF]
Ann BotPatel N, Budke JM, Bainard JD.
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Dynamics of Gene Loss following Ancient Whole-Genome Duplication in the Cryptic Paramecium Complex. [PDF]
Mol Biol Evol, 2023 Gout JF +15 more
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The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
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Expression pattern of resynthesized allotetraploid Capsella is determined by hybridization, not whole-genome duplication. [PDF]
New Phytol, 2023 Duan T, Sicard A, Glémin S, Lascoux M.
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Evaluation of gene editing in CHO cells using the Cas‐CLOVER system
Biotechnology Progress, EarlyView.Abstract Recent advances in gene editing technologies have transformed the genetic engineering of Chinese hamster ovary (CHO) hosts, enabling the development of cell lines with improved stability and productivity. In this study, we employed the programmable nuclease (PN) Cas‐CLOVER to precisely target the Glutamine synthetase (GS) locus in CHO cells. A
Tiffany McLamarrah +13 more
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