Results 201 to 210 of about 155,374 (249)

Multi‐Omics Profiling Uncovers Predictive Factors for Tumor‐Infiltrating Lymphocyte Therapy in Ovarian Cancer

Journal of Clinical Laboratory Analysis, EarlyView.
We profiled tumors from 10 ovarian cancer patients with whole‐exome sequencing (WES), bulk RNA‐seq, and single‐cell RNA‐seq to uncover predictors of successful tumor‐infiltrating lymphocyte (TIL) isolation and expansion. TIL+ tumors exhibited enriched CD8+ Teff/Tem populations with distinctive metabolic activity, dendritic‐cell–skewed myeloid states ...
Xiuzhen Wang, Rui Hou, Jinguo Chen, Bo He, Peiwen Liu, Genhai Zhu, Lan Hong, Wenjun Zhu   +7 more
wiley   +1 more source

Cross-species single-nucleus analysis reveals the potential role of whole-genome duplication in the evolution of maize flower development. [PDF]

BMC Genomics
Feng H, Fan W, Liu M, Huang J, Li B, Sang Q, Song B.   +6 more
europepmc   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

Molecular Dating of the Teleost Whole Genome Duplication (3R) Is Compatible With the Expectations of Delayed Rediploidization. [PDF]

Genome Biol Evol
Qi M, Clark J, Moody ERR, Pisani D, Donoghue PCJ.   +4 more
europepmc   +1 more source

Discovery of novel conserved peptide domains by ortholog comparison within plant multi-protein families [PDF]

, 2005
Panstruga, R.
core   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

wgd v2: a suite of tools to uncover and date ancient polyploidy and whole-genome duplication. [PDF]

Bioinformatics
Chen H, Zwaenepoel A, Van de Peer Y.
europepmc   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius, David B. Mark Welch, Holger Herlyn   +2 more
wiley   +1 more source

Esterification enhances carotenoid retention during bread‐making

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Carotenoids are plant‐derived antioxidants that contribute to human health and represent key quality traits in wheat‐based foods. However, they are highly unstable and prone to degradation during processing. Xanthophyll esterification has been identified as a natural mechanism that enhances carotenoid stability during grain storage.
María D Requena‐Ramírez, Cristina Rodríguez‐Suárez, Dámaso Hornero‐Méndez, Sergio G Atienza   +3 more
wiley   +1 more source

Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication. [PDF]

Dev Cell
Guerrero Zuniga A, Aikin TJ, McKenney C, Lendner Y, Phung A, Hook PW, Meltzer A, Timp W, Regot S.   +8 more
europepmc   +1 more source