Results 121 to 130 of about 1,170,509 (350)

A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome [PDF]

open access: yes, 2015
Citation: Chapman, J. A., Mascher, M., Buluç, A., Barry, K., Georganas, E., Session, A., . . . Rokhsar, D. S. (2015). A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome. Genome Biology, 16(1). doi:10.1186/s13059-
A Graner   +83 more
core   +5 more sources

Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

open access: yesNature Communications, 2019
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and breed-associated behaviors resulting from human selective pressures.
J. Plassais   +8 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Data on whole genome sequencing of extrapulmonary tuberculosis clinical isolates from India

open access: yesData in Brief, 2018
This article describes the whole genome sequencing data from 5 extrapulmonary tuberculosis clinical isolates. The whole genome sequencing was carried out on Illumina MiSeq platform to identify single nucleotide variations (SNVs) associated with drug ...
Jayshree Advani   +13 more
doaj   +1 more source

Author Correction: Estimation of the mutation rate of Mycobacterium tuberculosis in cases with recurrent tuberculosis using whole genome sequencing [PDF]

open access: gold, 2023
Jéssica Comín   +10 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA

open access: yesNature Communications
Analysis of DNA methylation in cell-free DNA reveals clinically relevant biomarkers but requires specialized protocols such as whole-genome bisulfite sequencing.
Yaping Liu   +16 more
doaj   +1 more source

Benchmarking of Nanopore R10.4 and R9.4.1 flow cells in single-cell whole-genome amplification and whole-genome shotgun sequencing.

open access: yesComputational and Structural Biotechnology Journal, 2023
Y. Ni   +4 more
semanticscholar   +1 more source

Whole-genome-sequencing of triple negative breast cancers in a population-based clinical study

open access: yesNature Network Boston, 2019
Whole-genome sequencing (WGS) brings comprehensive insights to cancer genome interpretation. To explore the clinical value of WGS, we sequenced 254 triple-negative breast cancers (TNBCs) for which associated treatment and outcome data were collected ...
J. Staaf   +20 more
semanticscholar   +1 more source

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