Results 191 to 200 of about 533,077 (310)

Enabling whole genome sequencing analysis from FFPE specimens in clinical oncology. [PDF]

Nat Commun
Domenico D, Gundem G, Levine MF, Arango-Ossa JE, Robbe P, Asimomitis G, Cobbs C, Stockfisch E, O'Donohue T, Brierley C, Senz J, Cochrane D, Mohibullah N, Bhanot U, Silber J, Shukla N, Shah SP, Weigelt B, Zivanovic O, McPherson A, Schuh A, Kung AL, Papaemmanuil E.   +22 more
europepmc   +1 more source

Identification and characterization of a male-specific region in largemouth bass (Micropterus Salmoides) by whole-genome sequencing, resequencing and genomics comparison [PDF]

Xinhui Zhang, Junjian Dong, Zhiqiang Ruan, Fengying Gao, Wenchuan Zhou, Xinxin You, Jieming Chen, Qiong Shi, Xing Ye, Chengfei Sun   +9 more
openalex   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Clinical use of whole-genome sequencing in children with developmental delay or intellectual disability. [PDF]

BMC Med Genomics
Xu J, Xu Y, Su W, Chen L, Wang Y, Li H.
europepmc   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Accurate and Cost-Efficient Whole Genome Sequencing of Hepatitis B Virus Using Nanopore. [PDF]

J Med Virol
Stenbäck JB, Schmidt D, Noborg U, Gustafsson J, Norberg P, Andersson ME, Fu MX, Harvala H, Ringlander J.   +8 more
europepmc   +1 more source

Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials

Advanced Science, EarlyView.
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang, Yiran Fang, Xiatong Huang, Guichuang Ma, Qianqian Mao, Xiansheng Lu, Guangda Rong, Yunfang Yu, Yuanyuan Wang, Zhenhua Huang, Huiying Sun, Jiani Wu, Wenchao Gu, Na Huang, Jianhua Wu, Rui Zhou, Xiaoxiang Rong, Siting Zheng, Shaowei Li, Gaofeng Wang, Ling Wang, Wenjun Qiu, Luyang Jiang, Peng Luo, Yonggang Liu, Jianping Bin, Yulin Liao, Min Shi, Zuqiang Wu, Jiguang Wang, Wangjun Liao, Gang Chen, Dongqiang Zeng   +32 more
wiley   +1 more source

Whole genome sequencing-based analysis of genetic predisposition to adult glioblastoma. [PDF]

NPJ Genom Med
van Opijnen MP, van Valkengoed DR, de Ligt J, de Vos FYF, Broekman MLD, Cuppen E, Koster R.   +6 more
europepmc   +1 more source

Additional file 2 of Population analysis of the Korean native duck using whole-genome sequencing data

, 2020
Daehwan Lee, Jongin Lee, Kang-Neung Heo, Kisang Kwon, Youngbeen Moon, Dajeong Lim, Kyung‐Tai Lee, Jaebum Kim   +7 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source