Results 211 to 220 of about 567,748 (308)

Whole genome sequencing for epidemiological studies of tuberculosis: a systematic review of reporting practices and factors associated with reporting quality of STROME-ID

, 2020
Brianna Cheng
openalex   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Leveraging whole-genome sequencing for microbial contamination tracking and risk assessment in pharmaceutical manufacturing. [PDF]

Front Microbiol
Li Q, Deng D, Dou X, Chen X, Duan X, Wang T, Song M.   +6 more
europepmc   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Additional file 3: Table S3. of Whole genome sequencing identifies missense mutation in MTBP in Shar-Pei affected with Autoinflammatory Disease (SPAID)

, 2017
Julia Metzger, Anna M. Nolte, Ann-Kathrin Uhde, Marion Hewicker-Trautwein, O. Distl   +4 more
openalex   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Tumor Whole-Genome Sequencing for Prediction of Venous Thromboembolism in Patients With Metastasized Solid Cancer. [PDF]

Circ Genom Precis Med
Mulder FI, Guman NAM, van Riet J, van Geffen RJ, van Haaps TF, Hovsepjan V, van Laarhoven HWM, Cirkel GA, de Vos FYFL, Westgeest HM, Beerepoot LV, de Vos-Geelen J, Labots M, Hamberg P, Vulink AJE, Los M, Zwinderman AH, Robbrecht DGJ, de Jonge MJA, Büller HR, Kamphuisen PW, Ferwerda B, Steeghs N, van Es N.   +23 more
europepmc   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

Advanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu, Yulu Yang, Zhiqi Hao, Jing Xu, Huibo Zhao, Qiang Zhang, Deyong Ren, Xia Li, Guojun Dong, Lan Shen, Li Zhu, Jiang Hu, Zhenyu Gao, Qing Li, Qian Qian, Guangheng Zhang   +15 more
wiley   +1 more source

A comparative review of three cloud-based platforms for microbial whole genome sequencing analysis. [PDF]

Antimicrob Steward Healthc Epidemiol
Hwang M, Choi H, Chatterjee P, Jinadatha C.   +3 more
europepmc   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source