Results 51 to 60 of about 3,777,350 (304)

Description of mpox reinfection by whole genome sequencing

open access: yesInternational Journal of Infectious Diseases, 2023
Several possible mpox reinfections have been reported, however, the debate on whether these are confirmed reinfections remains open.A 30-year-old male living with HIV and a history of single-dose mpox vaccination, first diagnosed with mpox in September ...
Javier Martínez-Sanz   +7 more
doaj   +1 more source

Optical mapping as a routine tool for bacterial genome sequence finishing [PDF]

open access: yes, 2007
Background: In sequencing the genomes of two Xenorhabdus species, we encountered a large number of sequence repeats and assembly anomalies that stalled finishing efforts.
Norton, S.   +57 more
core   +1 more source

Whole genome sequencing of breast cancer [PDF]

open access: yesAPMIS, 2019
Breast cancer was the first to take advantage of targeted therapy using endocrine therapy, and for up to 20% of all breast cancer patients a further significant improvement has been obtained by HER2‐targeted therapy. Greater insight in precision medicine is to some extent driven by technical and computational progress, with the first wave of a true ...
Rossing, Maria   +3 more
openaire   +4 more sources

Bioinformatics' approaches to detect genetic variation in whole genome sequencing data [PDF]

open access: yes, 2010
Current genetic marker repositories are not sufficient or even are completely lacking for most farm animals. However, genetic markers are essential for the development of a research tool facilitating discovery of genetic factors that contribute to ...
Kerstens, H.H.D.
core  

Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals [PDF]

open access: yes, 2014
Objectives Staphylococcus haemolyticus is an emerging cause of nosocomial infections, primarily affecting immunocompromised patients. A comparative genomic analysis was performed on clinical S.
Kahlke, Tim   +19 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Whole-genome sequence-based analysis of thyroid function. [PDF]

open access: yes, 2015
Normal thyroid function is essential for health, but its genetic architecture remains poorly understood. Here, for the heritable thyroid traits thyrotropin (TSH) and free thyroxine (FT4), we analyse whole-genome sequence data from the UK10K project (N=2 ...
Paternoster, Lavinia   +635 more
core   +1 more source

Whole-genome sequencing analysis of semi-supercentenarians

open access: yeseLife, 2021
Extreme longevity is the paradigm of healthy aging as individuals who reached the extreme decades of human life avoided or largely postponed all major age-related diseases.
Paolo Garagnani   +34 more
doaj   +1 more source

Multi-Platform Next-Generation Sequencing of the Domestic Turkey (Meleagris gallopavo): Genome Assembly and Analysis [PDF]

open access: yes, 2010
A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo).
Kent M Reed   +405 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

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