Results 101 to 110 of about 933,712 (305)

Estimated breeding values and association mapping for persistency and total milk yield using natural cubic smoothing splines [PDF]

, 2009
Background For dairy producers, a reliable description of lactation curves is a valuable tool for management and selection. From a breeding and production viewpoint, milk yield persistency and total milk yield are important traits.
Klara L Verbyla, Arunas P Verbyla, M Grossman, IM White, T Druet, JCM Dekkers, J Appuhamy, B Harder, WP Jones, BL Muir, K Togashi, K Togashi, N Gengler, T Druet, K Togashi, JB Cole, JB Cole, H Kiiveri, H Kiiveri, AP Verbyla, JI Weller, AB Samoré, JY Dai, AB Smith, AP Verbyla, PJ Green, IMS White, A Frensham, AR Gilmour, R Development Core Team, JH Jakobsen, R Rekaya, F Mekus, EL Sherman, Q Xiao, KM Rasmussen, D Yamaji, MS Ashwell, J Nadesalingam, J Kucerova   +39 more
core   +2 more sources

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

Protease Activities of Semi-purified Pseudomonas fluorescensin Protein Degradation of Pasteurized Milk at Storage

Journal of Biological Researches, 2012
Protein on stored milks spoiled due to protease activities of Pseudomonas fluorescens. To know protease effect on milks, protease activities of semi-purified P. fluorescens on protein degradation in stored pasteurized milks were detected.
Tatik Khusniati, Irma Normalia
doaj   +1 more source

A comparison of feeding reconstituted and dried milk upon the growth and carcass composition of calves [PDF]

, 1972
1. The live-weight gain, carcass weight, edible carcass composition, efficiency of food conversion, and roughage intake were measured in three groups of calves fed for 87 d.
Pryor, W. J., Ternouth, J. H.
core   +1 more source

The Fortification of Whole Milk and Skimmilk

Journal of Dairy Science, 1954
A discussion of milk fortification calls for consideration of the interests of both consumers and the dairy industry. The consumer is vitally interested in having an adequate supply of milk at a reasonable cost. He also is interested in any measures proposed for its modification.
openaire   +1 more source

THE GREATEST MENACE TO WHOLE MILK IN CITIES' SUPPLY. [PDF]

JAMA: The Journal of the American Medical Association, 1907
The terms employed in a definition of milk vary with the view point of the scientist and the phase of the subject emphasized. For the present purpose the following, gleaned from various sources, will answer every need: Milk is a normal animal secretion forming a perfect emulsion and containing, besides fat globules in suspension, albumin, sugar and ...
openaire   +2 more sources

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

Advanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao, Dalin Chen, Ziyi Zhang, Jingxuan Ren, Chengcheng Zhao, Shengfang Wang, Mengyu Shang, Dawei Jiang, Yinuo Li, Su'an Tang, Kai Li, Xiaohui Zhang, Xiaogang Wang   +12 more
wiley   +1 more source

Effect of vitamin E and selenium and different types of milk on health and growth of organic goat kids [PDF]

, 2012
Newborn goat kids are low in blood levels of vitamin E and selenium. Not known is how this affects health and growth of the kids. In a study on an organic farm 40 kids were allotted to 4 groups.
Eekeren, Nick van, Govaerts, Wim, Smolders, Gidi   +2 more
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source